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      • Open Access Article

        1 - Lameness, an ongoing threat to dairy farms
        Ahmadreza Mohamadnia Amir Nejati
        Lameness is one of the most important factors causing economic loss in dairy farms. Pain and discomfort following lameness are the main causes of direct and indirect economic losses. Overall situation of dairy farming and dairy products over the world and Iran is review More
        Lameness is one of the most important factors causing economic loss in dairy farms. Pain and discomfort following lameness are the main causes of direct and indirect economic losses. Overall situation of dairy farming and dairy products over the world and Iran is reviewed in this article. A general look at economic loss cycles, different discomfort and health issues that may caused by lameness are the main topics that were reviewed in this article. Data recording is one of the most important factors that should be considered in any analysis. Current methods of data recording in hoof trimming chute, including paper works and usage of excel sheets and other software were reviewed. General concepts of Farsi language android application for hoof data recording introduced and analysed. Manuscript profile
      • Open Access Article

        2 - Epidemiology of lameness; economic importance, prevalence and incidence
        Marzieh Faezi Reyhaneh Sangtarash
        Herd health and comprehensive preventive medicine were notified since the last half of 20th century, as the farmers were better educated and the value of individual animals relative to veterinary fees has decreased. Restricted attention had been given to the above idea More
        Herd health and comprehensive preventive medicine were notified since the last half of 20th century, as the farmers were better educated and the value of individual animals relative to veterinary fees has decreased. Restricted attention had been given to the above idea leads to misunderstanding of infectious and non-infectious diseases. Currently, veterinarians must support herd health programs designed to increase production by preventing disease, rather than just dispensing traditional treatment to clinically sick animals. Lameness as one of the costliest disorders in dairy herds, needs special attention. Both preventive costs (such as hoof trimming costs) and the losses due to heifer replacements and milk yield reduction should be counted as the economic losses of a disease. Indeed, local data play an important role in estimating lameness losses. Calculating measures of morbidity is a key point that helps the veterinarian and the farmer to know about the farm condition. So, in this article the economic importance of lameness and the concept of prevalence and incidence of it were reviewed. At the end there are some information about the prevalence and incidence of lameness in Iran and some other countries. Manuscript profile
      • Open Access Article

        3 - Risk factors for cattle lameness
        Ahmadreza Mohamadnia
        Lameness and its consequences are one the most important causes of economic losses in dairy farming. Lameness is a multifactorial condition that can be managed by knowing its risk factors and their importance in specific farms and conditions. Current article focusses on More
        Lameness and its consequences are one the most important causes of economic losses in dairy farming. Lameness is a multifactorial condition that can be managed by knowing its risk factors and their importance in specific farms and conditions. Current article focusses on understanding value of causative agents and risk factors in a condition like lameness and evaluating risk factors in dairy farms. Risk factors were classified into farm building or environment factors (Top roof of the barns and its slop and height, flooring and its drainage, distance to milking parlour, milking parlour collecting area, alleys and foot bathes) Managerial factors (Nutrition and feeding, overstocking, herd composition, days in milk, cow movements in the herd, slurry cleaning and drainage, bedding) environment (Temperature, humidity, raining, wind, altitude, heat stress management) and cow factors (body condition scoring, milk production, concurrent diseases, time budgeting). Each factor was analysed in Iran’s dairy farming situation and applied methods of its management were discussed. Manuscript profile
      • Open Access Article

        4 - Locomotion biomechanic and scoring in dairy farms
        Shabnaz mokhtarnazif Marzieh Faezi
        Lameness is one of the biggest challenges in modern dairy farm around the world. Lameness is defined as the clinical manifestation of painful disorder resulting in deviation from normal gait or posture. It usually happens following claw lesions, although internal and ex More
        Lameness is one of the biggest challenges in modern dairy farm around the world. Lameness is defined as the clinical manifestation of painful disorder resulting in deviation from normal gait or posture. It usually happens following claw lesions, although internal and external factors can affect it. Following herd size growing, farmer’s attention to individual cows has been reduced, therefore lameness diagnostic accrued in sever stages when treatments have the least effect on recovery and prevention. In this article, we try to understand pain basics and behavior changes related to it, using these changes in gait (i.e. back arch, walking speed, track up, head bob etc.) to assess different locomotion scoring systems and their use in dairy farms. Manuscript profile
      • Open Access Article

        5 - Cow comfort, a basis for lameness control
        Reyhaneh Sangtarash Shabnaz mokhtarnazif Ensiyeh Sajadyan jaghargh
        As the number of large-scale dairy farms increase dairy cow welfare has become a hot topic in recent years. This growing interest in animal welfare has motivated legislators to set new rules. The most important concerns regarding dairy cow welfare include whether the da More
        As the number of large-scale dairy farms increase dairy cow welfare has become a hot topic in recent years. This growing interest in animal welfare has motivated legislators to set new rules. The most important concerns regarding dairy cow welfare include whether the dairy cow is feeling well, functioning well, and performing natural behavior. Cow behavior and comfort level have a direct relationship with her production and health and cow comfort is one of the most important factors affecting the profitability of dairy farms due to its association with premature slaughter, survival of cows and reproductive life (number of complete lactations before slaughter). In this paper, we explained the concept of comfort in dairy cattle and its risk factors such as stall design, floor type, density, lameness and heat stress. Then the measures of cow comfort are introduced and the management considerations related to cattle comfort are discussed. Manuscript profile
      • Open Access Article

        6 - Metabolic disturbances predispose dairy cows to lameness
        Ali  Ghashghaii Mohammad Riahi
        During the recent decades, a considerable increase in milk production has occurred in dairy cows. But it has been accompanied by an unwanted increase in different diseases and disorders such as metabolic disturbances. Negative energy balance can cause ketosis and fatty More
        During the recent decades, a considerable increase in milk production has occurred in dairy cows. But it has been accompanied by an unwanted increase in different diseases and disorders such as metabolic disturbances. Negative energy balance can cause ketosis and fatty liver. Disturbances in macro-minerals such as calcium, phosphorus and magnesium, micro-minerals, proteins and enzymes often occur days to weeks after parturition. One or the most challenging post-parturient problem, is ruminal acidosis, that it mainly occurs due to changes in ration by using high fermentable carbohydrates to support milk production. All of mentioned disturbances can affect the hoof health and causing lameness in dairy cows. Laminitis is an important sequel of metabolic disturbances and ruminal acidosis in combination with inappropriate housing and management. Lameness can affect cow health and comfort, causing considerable economic losses in dairy industry. Manuscript profile
      • Open Access Article

        7 - Early diagnosis, an important success factor for treatment and control of lameness in cow
        Mohammad Reza  Aghchelou
        Lameness is one of the cases of culling of cows; also it causes weight and production loss because of pain and has a lot of therapeutic cost. In a study, the prevalence of lameness was estimated on average 2.2% in dairy herds by farmers. After more objective locomotion More
        Lameness is one of the cases of culling of cows; also it causes weight and production loss because of pain and has a lot of therapeutic cost. In a study, the prevalence of lameness was estimated on average 2.2% in dairy herds by farmers. After more objective locomotion scoring, the prevalence of lameness in same dairy herds was on average 8.1%. This matter shows importance of correct lameness diagnosis. The aim of this article is review of practical ways to early diagnosis of lameness in cows. Early diagnosis of lameness in cows is a very important matter because a cow that shows sever lameness have major problems and easily recognizable but a cow with lesser injury have a milder lameness and diagnosis is more difficult. In case of timely detection there is more success in treatment because of less injury. The best time for lameness diagnosis is the cows are monitored when they go to the milking parlor and return. The studies were shown usually farmers identify one of the four lamb cows because they spend a little time for this task, also the gait of cows change on different floors, like wet concrete, although it is difficult to diagnose the sound gait of mild lameness in many cases. In dairy cattle farms in addition to Body Condition Score which is done regularly, Locomotion Scoring is done regularly to allow early diagnosis of lameness. Manuscript profile
      • Open Access Article

        8 - Evaluation of Application of Probiotics in Periodontal Disease
        Yeganeh Mehrani
        Periodontal disease is the number one health problem in small animal patients. Periodontal disease is generally described in two stages, gingivitis and periodontitis. Periodontitis is the later stage of the disease process and is defined as an inflammatory disease of More
        Periodontal disease is the number one health problem in small animal patients. Periodontal disease is generally described in two stages, gingivitis and periodontitis. Periodontitis is the later stage of the disease process and is defined as an inflammatory disease of the deeper supporting structures of the tooth (periodontal ligament and alveolar bone) caused by microorganisms. It is caused by plaque buildup on teeth. The plaque is a smooth membrane, adhesive, contaminated with saliva bacteria and debris. Normal gingival tissues are pink in color, and have a thin, knife-like edge, with a smooth and regular texture. The first clinical sign of gingivitis is erythema of the gingiva. This is followed by edema, gingival bleeding during brushing or after chewing hard/rough toys, and halitosis. Probiotics are live micro-organisms administered in adequate amounts with beneficial health effects on the host.The presence of these organisms is an indicator of good periodontal health. Probiotics are effective in preventing candidiasis, reducing dental caries, and treating periodontal diseases. This article discusses the use of probiotics in the treatment of periodontal disease. Manuscript profile
      • Open Access Article

        9 - Dental Fracture Management in Cat and dog
        Faezeh Alipour
        Dogs and cats with broken or fractured teeth are an extremely common presentation for small animal practitioners. Every day, patients will be seen with a fractured tooth, dental caries, pulpal hemorrhage or some other dental complications. Many of these conditions are a More
        Dogs and cats with broken or fractured teeth are an extremely common presentation for small animal practitioners. Every day, patients will be seen with a fractured tooth, dental caries, pulpal hemorrhage or some other dental complications. Many of these conditions are a source of pain to the animal but often ignored by the owners. Extraction, usually, is not the only solution, because the teeth of small animals respond very well to advanced dental techniques, especially endodontic treatment. This paper discusses treatment options for fractured teeth including endodontic treatment, vital pulp therapy, surgical dental extraction. Manuscript profile
      • Open Access Article

        10 - دندانهای کشیده شده: دور ریختنی یا اتو گرافت فوری استخوانی؟
        Azin Tavakoli
        Extracted teeth are always considered as waste or debris. Tooth extraction is the most performed procedure in dentistry following cleaning and prophylaxis in small animals. The first indication of tooth extraction is advanced periodontal disease which the teeth attachme More
        Extracted teeth are always considered as waste or debris. Tooth extraction is the most performed procedure in dentistry following cleaning and prophylaxis in small animals. The first indication of tooth extraction is advanced periodontal disease which the teeth attachments loss occurs and the teeth could not be saved. Other indications include jaw and teeth fracture. In sever and refractory stomatitis, one of the recommended treatment is extraction of either rostral or even all teeth. Therefore, lots of extracted teeth as tissue similar to bone is available. In this article the role of extracted teeth in bone defects as readily available bone graft and regarded existed studies in literature will be reviewed. Manuscript profile
      • Open Access Article

        11 - An Introduction to Equine Dentistry; Necessity of Much More Consideration
        Alireza Raayat jahromi
        Dental problems are one of the main challenges in equine medicine and its management has a considerable effect on horse’s performance and profitability in equine industry. Considering the fact that prevention is better than treatment, a regular dental care program based More
        Dental problems are one of the main challenges in equine medicine and its management has a considerable effect on horse’s performance and profitability in equine industry. Considering the fact that prevention is better than treatment, a regular dental care program based on a scientific plan can lead to an early and definitive diagnosis; which results in a correct intervention and treatment. Dental and oral observation, necessary diagnostic and restraint equipment and instruments, attritional lesions and injuries will be explained and discussed. Finally, the current situation of equine dentistry in our country will be evaluated so that its necessity would be much more seriously considered. Manuscript profile
      • Open Access Article

        12 - A Review of Physiological Structures and Dental Disorders of Canids Using Radiography and Computed Tomography
        Ferdos Fekri Amir Zakian Mohsen  Abbasi Omid Zehtabvar Alireza Vajhi
        Canids are heterodont and diphyodont animals, which most of adult canids have 42 permanent teeth. Nowadays, attention to the oral and dental disorders in pets has gained a special region in veterinary medicine and on the top of these problems can be referred to dental i More
        Canids are heterodont and diphyodont animals, which most of adult canids have 42 permanent teeth. Nowadays, attention to the oral and dental disorders in pets has gained a special region in veterinary medicine and on the top of these problems can be referred to dental infections and other periodontal diseases. Anatomy and positioning of teeth and periodontal diseases also could be observed by diagnostic imaging techniques included radiography and CT-scan. Radiography is an effective method for dental examination with low-cost and fast execution times and can be performed during surgery. Although, computed tomography is high contrasted method in oral cavity examination that facilitates the diagnosis of multiple disease. Precise and detailed imaging of the region of interest even before changes become clinically apparent, the reduced examination time than oral radiography, 3D imaging in different views, but expensiveness and risks associated with anesthesia may be the restrictive factors. Manuscript profile
      • Open Access Article

        13 - Methods of Determining Age of Ruminants and Camelids by Using Dentition Patterns
        Sare Rezaei Amir Zakian Nima Moradpour
        Determining age is very important in domestic livestock because in addition to health, nutrition and grazing, from point of veterinary science some of the special disease it is age dependent and appear at certain ages. Therefore, knowing the age of domestic livestock fo More
        Determining age is very important in domestic livestock because in addition to health, nutrition and grazing, from point of veterinary science some of the special disease it is age dependent and appear at certain ages. Therefore, knowing the age of domestic livestock for the farmers both in terms of anticipating and preventing diseases and in terms of treatment is important and have a significant effect on exploitation, usage of animals in different services and the cost of farm. One of the methods of determining and judgment of the age in domestic animals is the use of the number, shape and date of tooth eruption. Therefore, the purpose of this paper is to provide practical and useful information for determining the age in ruminants and camelids, as reviewed by peer-reviewed articles and resources in recent years. We hope that this article will be useful to all students of veterinary medicine, active clinicians in large animals field, animal dentistry enthusiasts and other related businesses. Manuscript profile
      • Open Access Article

        14 - Vital Pulp Therapy an Appropriate Way to Save Tooth Life
        Bahareh Aghamohammadi Azin Tavakoli
        Vitality of dentin-pulp complex is essential for teeth health, so it’s the priority in clinical control strategies. Pulp vitality in caries treatment for young individuals or in primary teeth has vital importance .In traumatic injuries to the pulp, pulp may be exposed a More
        Vitality of dentin-pulp complex is essential for teeth health, so it’s the priority in clinical control strategies. Pulp vitality in caries treatment for young individuals or in primary teeth has vital importance .In traumatic injuries to the pulp, pulp may be exposed and would be necrotic or infected .In most cases pulpotomy would be the treatment choice for pulp exposures with pulpitis because of the reparative potential of remained tissue and biocompatibility of pulpotomy materials .Therefore development of biocompatible treatments for preservation of pulp vitality and tooth survival is important. Manuscript profile
      • Open Access Article

        15 - Laboratory diagnosis of liver disease in small animal practice
        Saba Ahmadi Morteza  Hasanabadi Mehrdad Mohri
        Today’s accurate diagnosis of disease requires using of different diagnostic and paraclinical methods. Diagnosis of liver disease was a serious challenge both in medicine and veterinary medicine from the past. Clinical biochemistry is one of the main parts of diagnostic More
        Today’s accurate diagnosis of disease requires using of different diagnostic and paraclinical methods. Diagnosis of liver disease was a serious challenge both in medicine and veterinary medicine from the past. Clinical biochemistry is one of the main parts of diagnostic methods. Liver function is evaluated by measuring the variables such as excreting and metabolic functions and enzymes. Because of large functional reserve of liver, symptoms of liver disease appear after loss of huge number of hepatocytes, therefore using of laboratory methods with high specificity and sensitivity could be helpful. None of existing laboratory methods has all characteristics mentioned above. It seems that using different laboratory methods of liver function beside other diagnostic methods such as sonography, cytology and … could be an appropriate approach for reaching a diagnosis of hepatobiliary disease. Current article reviews the perfect utility of liver function tests for general diagnosis of liver disease. Manuscript profile
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        16 - Overview of colic risk factors in horses
        Fattah  Iranmanesh Seyed Mahmoud  Shojaeian Amirsaeed  Samimi
        Gastrointestinal diseases are 50% of the problems and diseases that lead to death in adult horses. According to epidemiological studies, for every 100 horses per year, between 0.9 and 10 horses suffer from colic. The occurrence of colic varies between different farms an More
        Gastrointestinal diseases are 50% of the problems and diseases that lead to death in adult horses. According to epidemiological studies, for every 100 horses per year, between 0.9 and 10 horses suffer from colic. The occurrence of colic varies between different farms and even at different times in one farm. The occurrence of colic seems to be strongly influenced by the level of quality of herd management and horse maintenance throughout the year. This means that variation in the rate of occurrence originates more from management than from the breed of horses. Various factors such as breed, age, sex, history, nutrition, activities, infectious and parasitic problems and dental problems can increase the risk of colic in horses. For example, Arabian horses have been identified as predisposed to colic, and other Heidegger breeds such as the Thoroughbred and Warmblad, and standard-range horses, are at high risk for colic. In addition, stallions, especially castrated stallions, are more susceptible to colic. Changes in the type of concentrate consumed, the type of other feeds, the quality of forage and pasture are closely related to colic and their causative agents. Intestinal parasites, especially tapeworms and streptococci, are important risk factors for colic that can increase the risk Manuscript profile
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        17 - An overview of colic in horses
        Hanieh  Fatemi Hesamodin  Torghabeh Alireza  Kavehaski
        Colic or abdominal pain has long been one of the most important and challenging diseases that veterinarians in equine medicine have always dealt with. In colic, the choice of treatment method between medical and surgical has always been discussed. According to the findi More
        Colic or abdominal pain has long been one of the most important and challenging diseases that veterinarians in equine medicine have always dealt with. In colic, the choice of treatment method between medical and surgical has always been discussed. According to the findings of physical examinations such as pain, cardiovascular system, anal examination and other clinical and laboratory methods, the type of treatment method is selected and if necessary, by using appropriate techniques in cases that require surgery, the patient recovers. Finally, attention to the care required after this period is also one of the effective measures in the treatment of colic in horses. Manuscript profile
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        18 - Colic, update and advances
        Samaneh Ghasemi
        Colic as the most important equine disease requires emergency intervention to save patient’s life. Early diagnosis, management, and, treatment of affected horses will improve prognosis of treatment. Despite performed advances in diagnosis, anesthesia, surgery and postop More
        Colic as the most important equine disease requires emergency intervention to save patient’s life. Early diagnosis, management, and, treatment of affected horses will improve prognosis of treatment. Despite performed advances in diagnosis, anesthesia, surgery and postoperative care, colic is still a challenging concern in veterinary. Some of the most important advancements are presented in this article. Manuscript profile
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        19 - Laboratory diagnosis of renal diseases in small animal practice
        Morteza  Hasanabadi Saba Ahmadi Mehrdad Mohri
        Common tests for evaluating renal function include the measurement of urea and creatinine. However, indirect markers for the determination of GFR, such as Cystatin C and Symmetrical Dimethyl Arginine, are in developing. In the next step, for diagnosis and treatment, azo More
        Common tests for evaluating renal function include the measurement of urea and creatinine. However, indirect markers for the determination of GFR, such as Cystatin C and Symmetrical Dimethyl Arginine, are in developing. In the next step, for diagnosis and treatment, azotomia should be classified into one of the pre-renal, renal and post-renal groups. In the next step, it is necessary of categorizing the disorder to acute or chronic failure. Diagnosis of chronic or acute illness is done based on the history of the patient and physical examination. Weight loss and non-regenerative anemia may be signs of patients with CKD.Another useful test is urine analysis. A urine test prepared valuable information about azotemia and its causes. Additional tests are also available to diagnose kidney failure such as phosphorus, calcium, potassium, acid-base status, cholesterol, urine albumin, and GGT to urine creatinine ratio. Newbiomarkers such as Cystatin C, a Kidney injury molecule, and Neutrophil gelatinase-associated Lipocalinare also being studied and commercialized for early diagnosis of kidney disease, but they have not yet been clinically available for veterinary use. Manuscript profile
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        20 - Laboratory findings of acute pancreatitis in dogs and cats
        Niloufar  Abedi Mahdieh  Zaeemi
        Pancreatitis is the most common exocrine pancreatic disease in both dogs and cats. Acute pancreatitis is an inflammation with acute onset and characterized by necrosis and edema. Premature activation of trypsin in the acinar cells starts a cascade of reactions that re More
        Pancreatitis is the most common exocrine pancreatic disease in both dogs and cats. Acute pancreatitis is an inflammation with acute onset and characterized by necrosis and edema. Premature activation of trypsin in the acinar cells starts a cascade of reactions that result in autodigestion. Dogs are often presented with gastrointestinal signs, whereas lethargy and anorexia are the most commonly observed symptoms in cats. Acute pancreatitis may cause cardiovascular shock, disseminated intravascular coagulation or disability of multi organs and/or death. Diagnosing acute pancreatitis in dogs and cats is difficult. Several diagnostic methods have been proposed for the diagnosis of pancreatitis over the past few years, most of which are not applicable due to poor performance, inaccessibility or aggressiveness. Besides, many radiographic methods are used yet none of them are efficient except ultrasonography. Although several laboratory tests including measurement of hematology and biochemistry factors are available, none of them are specific for pancreatitis and they are merely beneficial in rejecting other diseases. The aim of this study was to investigate the more specific diagnostic tests for acute pancreatitis in small animals. Manuscript profile
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        21 - Thyroid glands: diseases and laboratory diagnosis in small animals
        Maedeh Ghari Niloufar  Abedi Mohammad Heidarpour
        Thyroid diseases are among the most common endocrine disorders in small animals. Hypothyroidism is a common disease in dogs, but spontaneous hypothyroidism is very rare in adult cats. Hyperthyroidism is one of the most common diseases of cats and is uncommon in dogs. Hy More
        Thyroid diseases are among the most common endocrine disorders in small animals. Hypothyroidism is a common disease in dogs, but spontaneous hypothyroidism is very rare in adult cats. Hyperthyroidism is one of the most common diseases of cats and is uncommon in dogs. Hypothyroidism is primarily a disease of middle aged to old dogs with clinical signs including weight gain to obesity, lethargy, dull haircoat, cold intolerance detected as heat-seeking behavior, decreased libido, reproductive failure, alopecia with no pruritus, and hyperpigmentation in areas of alopecia. Laboratory abnormalities may include mild anemia, increased liver enzymes and increases in muscle enzymes (CPK). Hypertriglyceridemia and hyperlipidemia occurs in a majority of cases. Hypercholesterolemia is seen in approximately 80% of hypothyroid dogs and a serum cholesterol concentration greater than 500 mg/dL is very suggestive of hypothyroidism. Basal concentration of total T4 should be the initial endocrine diagnostic test utilized when hypothyroidism is suspected. However, approximately 20% of dogs without hypothyroidism may also have decreased TT4. In addition, total T4 may be in the normal range in about 10% of dogs with hypothyroidism. Therefore, it is important to measure other endocrine tests (free T4 and TSH concentrations). The challenging cases may require more intensive diagnostic procedures such as repeat testing in 4 weeks and/or stimulation tests (TSH or TRH). Hyperthyroidism is the most common endocrine disease of cats. Hyperactivity, weight loss, and polyphagia in a middle aged to old cat are the most frequent clinical problems. Increase in one or more liver enzymes, azotemia, hyperphosphatemia and erythrocytosis are the most consistent lab abnormalities of the hyperthyroid cats. If a cat has some of the physical and clinical laboratory abnormalities characteristic of hyperthyroidism, and an increased TT4 concentration, it is diagnostic of hyperthyroidism and fT4 or any additional tests are not needed. When faced with conflicting clinical signs and lab data while trying to confirm a diagnosis of hyperthyroidism, other endocrine tests such as repeating total T4 in 1-2 weeks, free T4 concentration, T3 suppression test and/or stimulation tests (TSH or TRH) should be considered. Manuscript profile
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        22 - Biomarkers of myocardial and skeletal muscle diseases in small animals
        Maedeh Ghari Mahdieh  Zaeemi
        Muscle diseases can be either inherited or acquired that result from several different disease processes including; infectious, drug- and toxin-induced, and immune mediated, endocrine and metabolic disorders. Standard hematological and biochemical, immunologic, molecula More
        Muscle diseases can be either inherited or acquired that result from several different disease processes including; infectious, drug- and toxin-induced, and immune mediated, endocrine and metabolic disorders. Standard hematological and biochemical, immunologic, molecular, pathological tests are indicated to diagnosis and monitoring these diseases. From the biochemical tests, the serum activities of aspartate aminotransferase enzymes, lactate dehydrogenase, creatinine kinase, and serum concentration of lactate, myoglobin, troponins, natriuretic peptides, are measured. The aim of this study is to introduce biomarkers that used nowadays to detect skeletal muscle and myocardial damage in small animals. It also provides information on the structure, function, metabolism, reference values and applicability of these biomarkers to provide a better understanding of the health status of skeletal and myocardial muscles by choosing an appropriate biomarker. Manuscript profile
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        23 - Laboratory diagnosis of iron metabolism disorders in Dogs and Cat
        Masoume  Masoumi Verki Mahdieh  Zaeemi
        Iron is essential to virtually all living organisms and is integral to multiple metabolic functions. Disorders of iron in the body include iron deficiency anemia, anemia of inflammatory disease, and iron overload. This article summarizes iron metabolism and disorders as More
        Iron is essential to virtually all living organisms and is integral to multiple metabolic functions. Disorders of iron in the body include iron deficiency anemia, anemia of inflammatory disease, and iron overload. This article summarizes iron metabolism and disorders associated with iron metabolism in small animals and the diagnostic tests currently in use for assessing iron status are discussed. Manuscript profile
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        24 - An overview of the management of mild colic
        Fattah  Iranmanesh Fatemeh  Heydari Ehsanollah Sakhaee Reza Nikzad
        Colic is one of the most important problems affecting horses and affects 4 to 10% of horses annually. It is noteworthy that 80% of colic cases are either gaseous or of unknown origin that improve without treatment or with a simple treatment. Usually, about 5% of horses More
        Colic is one of the most important problems affecting horses and affects 4 to 10% of horses annually. It is noteworthy that 80% of colic cases are either gaseous or of unknown origin that improve without treatment or with a simple treatment. Usually, about 5% of horses develop mild colon accumulation in a mild form and respond to treatment, and less than 7% of colic cases require surgery. Horses that show mild colic symptoms have a better prognosis for survival, and ultimately in 13% of cases there is a chance of recurrence of symptoms. Manuscript profile
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        25 - Principles of oral and injectable fluid therapy in equine colic
        Fattah  Iranmanesh Fatemeh  Heydari Ehsanollah Sakhaee
        Fluid therapy is one of the most important parts of the treatment protocol for horses with colic. Fluid therapy methods include oral and intravenous administration. Although intravenous fluid intake is the most basic form of fluid therapy in horses with colic, prudent u More
        Fluid therapy is one of the most important parts of the treatment protocol for horses with colic. Fluid therapy methods include oral and intravenous administration. Although intravenous fluid intake is the most basic form of fluid therapy in horses with colic, prudent use of oral fluid therapy can be used as an adjunct or alternative treatment. Manuscript profile
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        26 - A review on the structure of the skin
        Omid Zehtabvar Reza Khoshvaght Fakhra  Borgheie
        Skin (also known as the integument) is the largest organ of the body accounting for 12% to 20% (different ratio in various texts) of total body weight. Skin consists of two basic regions, the superficial epidermis and deep dermis. Beneath the dermis is the subcutaneous More
        Skin (also known as the integument) is the largest organ of the body accounting for 12% to 20% (different ratio in various texts) of total body weight. Skin consists of two basic regions, the superficial epidermis and deep dermis. Beneath the dermis is the subcutaneous or hypodermis layer of loose connective tissue. Generally, the main architecture of the skin similar in all mammals, but there are differences between various species. The skin is thickest over the dorsal surface of the body and is thinnest on the ventral surface of the body. The skin could have ridges on its surface or be smooth in some areas. Epidermis consists of Stratum basale, Stratum spinosum, Stratum Granulosum, Stratum lucidum, Stratum corneum. Dermis consists of papillary and reticular layers and has a lot of blood and lymphatic vessels also sensitive and neurogenic receptors. Hair is a long, thin and elastic skin derivation that internal envelopment is from epidermis and loose connective tissue of external envelopment derived from dermis. Footpads are changed skin structures in cranial and caudal limbs. There are another structures like horn and hook that derived from skin. Abdominal cavity consists of these layers from inside to outside: skin, superficial fascia, skeletal muscles, deep fascia and serosa. Tunica serosa consists of a mesenchymal layer that forms from one layer of simple squamous epithelial cells and stroma connective tissue. Manuscript profile
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        27 - Inflammation role in wound management
        Mohsen Vahar Nasim Ghasemi
        The inflammatory phase is the body´s natural response to injury. After initial wounding, the blood vessels contract and a clot is formed. Followed by hemostasis has been achieved, blood vessels then dilated to allow essential cells, antibodies, white blood cells, growth More
        The inflammatory phase is the body´s natural response to injury. After initial wounding, the blood vessels contract and a clot is formed. Followed by hemostasis has been achieved, blood vessels then dilated to allow essential cells, antibodies, white blood cells, growth factors, enzymes and nutrients to reach the wound area. Erythema, heat, edema, pain and functional disturbance are the characteristic signs of inflammation that seen at this stage. The duration of the inflammatory phase usually lasts several days. Manuscript profile
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        28 - Different methods of debridement in open wounds
        Seyed Masoud  Rezvan
        Wound debridement in open wounds is one of the most necessary actions to be performed for wound healing achievement. It can reduce the amount of non-viable tissues, microbial contamination and foreign bodies in the wound’s bed. As a result, wound healing will be acceler More
        Wound debridement in open wounds is one of the most necessary actions to be performed for wound healing achievement. It can reduce the amount of non-viable tissues, microbial contamination and foreign bodies in the wound’s bed. As a result, wound healing will be accelerated and facilitated. There are different methods for wound debridement using various instruments or substances or even endogenous secretions. Each of these methods has its own benefits and drawbacks and for the best choice the wound condition evaluation, facilities and the performer’s ability should be considered. The key point is to choose the method with most positive and least negative effects on wound healing process. Manuscript profile
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        29 - The role of contraction and epithelialization in open wound management
        Vahid Shahbazi Nazanin  Samiee
        The two phenomena of wound contraction and reepithelialization which occur as stages of the repair phase in healing of the wound play an important role in closing the damaged site. Contraction is formed by the transformation of the modified fibroblast cells called myofi More
        The two phenomena of wound contraction and reepithelialization which occur as stages of the repair phase in healing of the wound play an important role in closing the damaged site. Contraction is formed by the transformation of the modified fibroblast cells called myofibroblasts, and these cells, through their tensile properties, pierce the wound's environment and cut the edges together, and after contacting the two healthy regions, this process stops. Epithelialization also covers the damaged area by migrating epithelial cells at the wound surface. These cells, by secretion of the enzymes, open their path of movement on the wound surface and, after reaching the same cells, stop and thus the location of the ulcer is covered and problems such as fluid loss and the entry of microbial objects to the body will be disappeared. Manuscript profile
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        30 - Pathophysiology of wound healing
        Hossein Gholami Behran Zamani Rad Saeed Farzad-Mohajeri
        Wound healing is an important concern in clinical medicine. Wound healing including skin wounds is a dynamic complicated procedure which involves many different molecular and cellular agents that occur after a tissue lesion in order to repair the injured tissue. Poor wo More
        Wound healing is an important concern in clinical medicine. Wound healing including skin wounds is a dynamic complicated procedure which involves many different molecular and cellular agents that occur after a tissue lesion in order to repair the injured tissue. Poor wound healing after trauma, surgery, or chronic disease such as diabetes affects human and animal life. Well understanding this process is necessary for developing therapeutic strategies and wound management to help treatment of normal healing procedure. The repair of wounded skin is included hemostasis and inflammation, proliferation, and maturation and remodeling. These steps have considerable overlaps with each other. Manuscript profile
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        31 - The role of platelet-rich plasma (PRP) in treatment of the canine osteoarthritis
        niloofar seydi Ali  Ghashghaii
        Osteoarthritis (OA) is a degenerative joint disease accompanied by a progressive reduction of extracellular matrices in joint cartilage and bone and, eventually, loss of joint function and excessive morbidity. OA has been reported in various animal spesies, such as can More
        Osteoarthritis (OA) is a degenerative joint disease accompanied by a progressive reduction of extracellular matrices in joint cartilage and bone and, eventually, loss of joint function and excessive morbidity. OA has been reported in various animal spesies, such as canine. During years, various therapeutic measurs have been used for treating the OA. The purpose of this article is to investigate the role of platelet-rich plasma (PRP) in treatment of the canine osteoarthritis. PRP is the concentration of platelets derived from the plasma portion of one’s own blood. It can be injected in the site of injury, or it can be made into a platelet-rich fibrin clot (PRFC) to use as a scaffold and source for sustained releasing of growth factors. These growth factors reduce the expression of inflammatory cytokines, which dampens the production of destructive matrix. In veterinary medicine, PRP has most often been reported for tendon/ligament injuries and osteoarthritis. The majority of the veterinary literature reporting on PRP involves its use in equine patients, and evidence in canine patients is few. In summary, PRP appears to be safe and potentially useful in treating a number of orthopedic conditions. In vitro data and clinical results in other species are encouraging Manuscript profile
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        32 - Isolation and Determination of Antibiotic Resistance of Salmonella and Staphylococcus Isolated from Dog and Cat Diets
        Ebrahim  Janmohammadi Firooz Mehdi  Sharifi Soltani Atefeh Bozorgi
        Bacterial contamination and widespread use of antibiotics lead to the emergence of antibiotic-resistant bacteria. The aim of this study was to isolate Salmonella and Staphylococcus from diets used for dog and cat and to determine their antibiotic resistance. 50 samples More
        Bacterial contamination and widespread use of antibiotics lead to the emergence of antibiotic-resistant bacteria. The aim of this study was to isolate Salmonella and Staphylococcus from diets used for dog and cat and to determine their antibiotic resistance. 50 samples of dog and cat dry diets were collected. For isolation of Salmonella, culture in liquid Selenite-F, Bismuth sulfite, xylose lysine deoxycholate (XLD) and Salmonella Chromogenic agar were used and for the detection of Staphylococcus, Baird-Parker and mannitol-salt agar. Antibiogram testing was performed by disk diffusion method. Data were analyzed using SPSS 16 software, chi-square test and independent t-test (p≤0.05). Salmonella and Staphylococcus infections were 72% and 20% in dog food and 26% and 80% in cat food, respectively. 100% of the dry bulk feed of cats infected with Salmonella and Staphylococcus and 100% of the samples of dry bulk feed of dogs were infected with Salmonella. 100% of Salmonella strains were resistant to all antibiotics. There was a significant relationship between the level of bacterial contamination and the type of diet (p≤0.05). The presence of bacteria along with antibiotic resistance was identified in this study. Hygiene principles and microbial evaluations are necessary to control and prevent food contamination with bacteria. Manuscript profile
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        33 - Anesthetic management differences between small animal and horse
        Nasser Vesal
        Veterinary anesthesia is a relatively new science that uses different drugs and techniques to provide optimal condition (analgesia, immobility, muscle relaxation and amnesia) to perform various medical, diagnostic and surgical procedures in domestic, exotic and wild ani More
        Veterinary anesthesia is a relatively new science that uses different drugs and techniques to provide optimal condition (analgesia, immobility, muscle relaxation and amnesia) to perform various medical, diagnostic and surgical procedures in domestic, exotic and wild animals. In order to perform a safe sedation, analgesia, local and general anesthesia, adequate scientific knowledge of anatomy, physiology and pharmacology of the species are required. The most common species that referred for surgical procedures are small animal (cat and dog) and horses. Although surgical procedure are also performed on ruminants, general anesthesia is not common in these species due to some specific reasons (economic costs, bloat, regurgitation and easily performed standing surgeries in cattle). There are several anatomical, physiological and pharmacological differences as well as difference in body weight and temperament between small animal and horses that should be considered before anesthesia. The present paper discusses the major differences that require appropriate preoperative preparation when conducting anesthesia in small animal and horses. Manuscript profile
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        34 - Surgical management of colic in horses: experiences report of the Surgical Section of Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman
        Mohamadmehdi oloumi Omid Azari Hadi Hasibi Amin Pydar Mohammad  Farajli Abbasi Reza Nikzad Mohammad Shahraki Hamidreza Savadkoohi Alborz Mirzadeh Hanieh  Fatemi Hesamodin Torghabe Alireza  Kavehaski
        From September 2016 to 2019, 74 horses with signs of colic were referred to the Veterinary Referral Hospital of Shahid Bahonar University of Kerman. In this article, surgical management of some of these cases from the time of admission to discharge is described.
        From September 2016 to 2019, 74 horses with signs of colic were referred to the Veterinary Referral Hospital of Shahid Bahonar University of Kerman. In this article, surgical management of some of these cases from the time of admission to discharge is described. Manuscript profile
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        35 - Methods of wound management
        Melika Danesh Mahdi ghamsari Farajolah Adib Hashemi
        The integrity of healthy skin plays a crucial role in maintaining physiological homeostasis of the body. Wound management is the most important issue in medicine and constantly evolving with the advances. The overall increase of different kind of wounds, and chronic w More
        The integrity of healthy skin plays a crucial role in maintaining physiological homeostasis of the body. Wound management is the most important issue in medicine and constantly evolving with the advances. The overall increase of different kind of wounds, and chronic wounds take a long time to heal makes wound care more complicated and important. Thus, there is a growing need to use of best methods for wound healing therapies to improve cutaneous wound healing. This article offers an overview of common methods of wound management, including physical, chemical and biological methods. Manuscript profile
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        36 - Application of stem cells and tissue engineering in wound management
        Saeed Farzad-Mohajeri Mahdi ghamsari
        Optimum healing of a cutaneous wound involves a cascade of biologic cellular and molecular processes. When the normal biological process fails for any reason, healing process can cease resulting in chronic wounds. In Addition, the body cannot repair some extensive wou More
        Optimum healing of a cutaneous wound involves a cascade of biologic cellular and molecular processes. When the normal biological process fails for any reason, healing process can cease resulting in chronic wounds. In Addition, the body cannot repair some extensive wounds without problem. These Issues surrounding wound healing as well as increased medical healthcare in this field, developed novel wound therapies. Regardless of the type of these specific advanced wound care methods, the ideal goal would be to regenerate tissues such that both the structural and functional properties of the wounded tissue are restored to the levels before injury. Tissue engineering and stem cells may be the solution. A range of cell based therapies and tissue engineered scaffolds have begun to cross the rift from bench to bedside. These therapies have been heralded as a promising means by which to surpass current limitations in wound management. The wide differentiation potential of stem cells allows for the possibility of regenerating lost or damaged skin, while their ability to immunomodulate the wound bed from afar suggests that their clinical applications need not be restricted to direct tissue formation. The data suggests that the appropriate application of stem cells and scaffolds can accelerate wound healing. The clinical utility of stem cells and tissue engineering has been demonstrated across dozens of clinical trials in wound therapy. Manuscript profile
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        37 - New perspectives in wound management and treatment
        Saeed Farzad-Mohajeri Mahdi ghamsari Farzad Hayati
        Wound healing has been a major medical challenge in recent decades and it increase motivation of researchers to develop various therapeutic approaches. Along with the latest developments in science and technology, diverse approaches have been created and improved. Alt More
        Wound healing has been a major medical challenge in recent decades and it increase motivation of researchers to develop various therapeutic approaches. Along with the latest developments in science and technology, diverse approaches have been created and improved. Although Traditional management, including wound dressings and skin grafts, is still commonly used in current practice but newer technologies found their roles in wound management, such as using stem cells in skin grafts or combining traditional treatments with anti-bacterial nanoparticles. Various upcoming technologies, such as nanotechnology, biotechnology, stem cell therapy and telemedicine have emerged in recent years and are being used to assist wound healing, or even to replace traditional methods. However, many of these methods still lack assessment by large-scale studies and extensive application. Also, studies should design to explore cost-effectiveness, conveniency and efficacy of them. In this review, authors focus on and summarize recent developments involving hi-tech therapeutic methods that lead to both rapid healing and better cosmetic results. Manuscript profile
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        38 - Wound management in the limb of the horse
        Abbas Raisi Khosro Safari
        The two phenomena of wound contraction and reepithelialization which occur as stages of the repair phase in healing of the wound play an important role in closing the damaged site. Contraction is formed by the transformation of the modified fibroblast cells called myo More
        The two phenomena of wound contraction and reepithelialization which occur as stages of the repair phase in healing of the wound play an important role in closing the damaged site. Contraction is formed by the transformation of the modified fibroblast cells called myofibroblasts, and these cells, through their tensile properties, pierce the wound's environment and cut the edges together, and after contacting the two healthy regions, this process stops. Epithelialization also covers the damaged area by migrating epithelial cells at the wound surface. These cells, by secretion of the enzymes, open their path of movement on the wound surface and, after reaching the same cells, stop and thus the location of the ulcer is covered and problems such as fluid loss and the entry of microbial objects to the body will be disappeared. Manuscript profile
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        39 - Laparoscopic ovariectomy in dogs: a comparison of the Ligasure, Ultrasound, Bipolar, and Ligature methods
        Mohammad Yasan Bangash Mir Sepehr Pedram Sanaz Banifazl Mohammad Molazem Maryam Iran Manesh Fariba Khaki Yazdan Aryazand
        Introduction: Laparoscopic ovariectomy is one of the common procedures performed in adult female dogs. The objective of this study was to compare the intraoperative and postoperative effects of laparoscopic ovariectomy with four hemostasis methods including Ligasure(LS) More
        Introduction: Laparoscopic ovariectomy is one of the common procedures performed in adult female dogs. The objective of this study was to compare the intraoperative and postoperative effects of laparoscopic ovariectomy with four hemostasis methods including Ligasure(LS), Ultrasound scalpel(US), Bipolar(BP) electrosurgery, and ligature(LT). Materials and Methods: 9 adult mix breed female dogs divided into four groups (LS, US, and LT(n=2); BP (n=3)). Total operation time(TT), Total hemostasis time(HT), presence of hemorrhage was recorded during surgery. In the 7th day objects euthanized to investigate abdominal cavity for gross pathologic changes such as presence of adhesion, and histopathological changes due to thermal damage in organs adjacent to anatomic region of ovaries such as uterine horns. Results: Both TT and HT significantly reduced in LS and US groups in comparison with BP group (P<0.05). TT and HT in LT group were significantly more than BP group. Minimum adhesion score were detected in LS and US groups (no significant difference) which were significantly lesser than BP group (P<0.05). In LT group granuloma around suture material were detected. Thermal damage on uterine horn were significantly higher in BP and LS groups (no significant difference) than US and LT(with no thermal injury) groups (p<0.05). Discussion and Conclusion: Application of easy, fast, safe method of hemostasis with minimal thermal damage and postoperative complications is mandatory in laparoscopic ovariectomy. Use of Ultrasonic scalpel in comparision with other methods was fast, and the most applicable with minimum thermal injury and postoperative complications in laparoscopic ovariectomy. Manuscript profile
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        40 - Arthroscopy in small animals
        Samaneh Ghasemi
        Application of minimally invasive surgeries are increasing in veterinary medicine. Joint disorders are among the most important cause for lameness in small animals, especially dogs. Arthroscopy is one of the techniques for diagnosing, treating and managing of joint inju More
        Application of minimally invasive surgeries are increasing in veterinary medicine. Joint disorders are among the most important cause for lameness in small animals, especially dogs. Arthroscopy is one of the techniques for diagnosing, treating and managing of joint injuries. Arthroscopy has advantages over arthrotomy. Arthroscopic surgery is used for management of different injuries in shoulder (glenohumeral), coxofemoral (hip), elbow, carpal and tarsal joints in small animals. Arthroscopy provides the best access to intra-articular structures. Also, post-operative cares, recovery, pain and infection are less than arthrotomy. The goal of this article is to review the uses of arthroscopy in small animals. Manuscript profile
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        41 - Introduce of a Simple and Minimally Invasive Approach for Access to Epidural Space
        Asma Asadian Mohammad mehdi Dehghan Majid Masudifard َAthena Salimi
        Background: Although various researches have been conducted to improve therapeutic strategies in resolving spinal cord injuries, robust clinical treatment is not yet available. Developing a standard animal model is essential before treatment. Objectives: The present st More
        Background: Although various researches have been conducted to improve therapeutic strategies in resolving spinal cord injuries, robust clinical treatment is not yet available. Developing a standard animal model is essential before treatment. Objectives: The present study was performed to introduce a simple, applicable, and minimally invasive approach for access to epidural space in cat. Methods: We used per-cutaneous approach from lumbosacral junction for stainless steel cannula insertion to the epidural space. CT-scan, conventional Magnetic Resonance Imaging, tractography, and behavioral evaluation were used to assess the correct position of cannula and neurological condition of the patient. Results: MRI results showed no significant change in signal intensity index of neural structures under lumbosacral junction. These observations were further supported by tractography, and also behavioral examination during study. Conclusions: We found that per-cutaneous approach from lumbosacral junction is a simple and applicable approach which has no side effects and artifact formation in MRI evaluation. Manuscript profile
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        42 - Inflammation and arcing (BOWED TENDON) of the superficial flexor tendon (SDF)
        Saeed Azizi Mahmoodjigh Nima Mozafari Farshid Davoudi
        Among the flexor tendons in the horse's limbs, the superficial digital flexor tendon is more prone to damage than the deep digital flexor tendon. SDF tendonitis is a common injury in event horses. Recovery of superficial digital flexor tendon (SDFT) injuries is slow, bu More
        Among the flexor tendons in the horse's limbs, the superficial digital flexor tendon is more prone to damage than the deep digital flexor tendon. SDF tendonitis is a common injury in event horses. Recovery of superficial digital flexor tendon (SDFT) injuries is slow, but re-injury is likely. SDF tendon injuries are more common in the forelimb. Flexor tendon injuries are due to strain on the tendon or a direct trauma. Tendon damage vary from inflammation and pain to complete rupture of the tendon. Injuries caused by strain are associated with swelling that require ultrasound assessment to confirm the diagnosis. Treatment for these injuries includes anti-inflammatory treatment, which is initially followed by a rehabilitation program. In cases where drug treatment is not responsive, surgical procedures including tendon splitting and superior check ligament desmotomy can be used. In this study, we briefly review the tendonitis of the superficial digital flexor tendon, etiology, clinical signs, diagnosis, treatment and prognosis. Manuscript profile
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        43 - Horse limb ligaments, injuries and its treatment
        Rahim Mohammadi Farshid Davoodi
        Disorders and problems of the ligaments of the motor limbs of horse are among the things that severely affect the performance of the horse and cause lameness. Early diagnosis, management and treatment measures will improve the prognosis of treatment. Damage to the ligam More
        Disorders and problems of the ligaments of the motor limbs of horse are among the things that severely affect the performance of the horse and cause lameness. Early diagnosis, management and treatment measures will improve the prognosis of treatment. Damage to the ligaments of the suspensory apparatus, which includes the suspensory ligament and distal sesamoidean ligaments, is one of the most important ligament injuries of the fore and hind limbs. Despite advances in horse care, ligament injuries continue to occur. In this paper, we review the types of ligament problems in the limbs, etiology, clinical signs, examination, diagnosis, treatment and prognosis. Manuscript profile
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        44 - A review of the most common tendon sheath injuries in horses
        Rahim Mohammadi Nima Mozafari
        Tendon sheath is a connective tissue that main function is to protect the tendon in the areas that are most vulnerable to damage. One of the relatively common causes of lameness and abnormalities in the limb of horses is tendon sheath damage. Injuries to the digital ten More
        Tendon sheath is a connective tissue that main function is to protect the tendon in the areas that are most vulnerable to damage. One of the relatively common causes of lameness and abnormalities in the limb of horses is tendon sheath damage. Injuries to the digital tendon sheath, tarsus, and carp are more common than tendon sheaths in other parts of the limbs. Lameness and swelling at the site of the lesion are common clinical findings in many tendon sheath injuries. Primary diagnosis of tendon sheath inflammation is possible with the help of animal history and clinical signs. The use of diagnostic tools, especially diagnostic imaging, is very useful for definitive diagnosis and identifying the primary cause of the disorders or damage to the surrounding tissues. Complete treatment should be done after identifying the underlying cause of sheath inflammation, although treatments such as rest, the use of anti-inflammatory drugs, and cold therapy are effective in reducing inflammation and improving clinical signs. Manuscript profile
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        45 - Nanoparticles for Tendon Healing and Regeneration
        sara javanmardi Dara Azizi
        Tendon tissue has limited regeneration potential and usually the consequent formation of scar tissue causes inferior mechanical properties. Nanoparticles could be used in different way to improve tendon healing and regeneration, ranging from scaffolds manufacturing (inc More
        Tendon tissue has limited regeneration potential and usually the consequent formation of scar tissue causes inferior mechanical properties. Nanoparticles could be used in different way to improve tendon healing and regeneration, ranging from scaffolds manufacturing (increasing the strength and endurance or anti-adhesions, anti-microbial, and ante inflammatory properties) to gene therapy. This paper aims to summarize the most relevant studies showing the potential application of nanoparticles for tendon tissue regeneration. Manuscript profile
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        46 - Tendon, tendon disorders and Cell therapy in tendon
        Mehdi Behfar Mohammad Hossein Farjah
        The tendon is a firm fibrous band of connective tissue that connects muscle to bone. This structure has the ability to transfer mechanical forces resulting from muscle contraction to the skeletal system. Tendinitis is a general term, often used to describe painful tendo More
        The tendon is a firm fibrous band of connective tissue that connects muscle to bone. This structure has the ability to transfer mechanical forces resulting from muscle contraction to the skeletal system. Tendinitis is a general term, often used to describe painful tendon situations due to constant stretching, overuse, degeneration, or poor tendon biomechanism. Tendinopathy is often the result of useless attempts by the body to regenerate a tendon, which a pathological conflict has led to a malfunction. Various treatments have been used to manage tendon disorders. Stem cells are divided into two categories. Embryonic cells (which are very potential but due to ethical considerations, limited studies have been done on them) and postnatal cells. Postnatal cells are divided into two categories, which include; Hematopoietic stem cells and mesenchymal stem cells. Mesenchymal stem cells have the ability to differentiate into multiple cells, including tenocytes, chondrocytes, and fibroblasts. these cells are a potential alternative to treating tendon lesions. This article presentan overview of the structure, biomechanics and disorders of tendon and, while pointing to the common therapies today, introduces stem cells , retrospective studies and possibility of using these cells in the optimal treatment of tendon disorders. Manuscript profile
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        47 - Induction of septic peritonitis with laparoscopic assisted cecal ligation and cauterization (CLC) in rabbit
        Mahdieh Katebian Mir Sepehr Pedram Majid Masudifard mehdi nasiri
        Sepsis is a complex and dynamic syndrome and it is a medical and economic challenge. To learn more about pathophysiology of this syndrome, animal models have been introduced. Poly microbial sepsis induced by cecal ligation and puncture is the gold standard model of this More
        Sepsis is a complex and dynamic syndrome and it is a medical and economic challenge. To learn more about pathophysiology of this syndrome, animal models have been introduced. Poly microbial sepsis induced by cecal ligation and puncture is the gold standard model of this condition. The purpose of this study was introducing a new method of septic peritonitis with laparoscopic assisted cecal ligation and cauterization (CLC) in rabbit model. This study included two groups of adult male New Zealand white rabbits: Control group (4rabbits): exploratory laparoscopy was performed and the cecum was grasped from the distal of ileocecal valve using an atraumatic forceps and pulled out from the trocar entry site. CLC group (4 rabbits): the cecum was ligated and two sites of cecum were cauterized from antimesenteric to mesenteric surface of cecum. Before and during 24 hours after the operation, heart rate, rectal temperature and respiratory rate of rabbits were monitored. Ultrasonography, CBC, peritoneal fluid analysis and bacterial culture was checked 24 hours after the surgery. Statistical analysis of the data in CLC group rabbits showed a significant increase in heart rate 6 and 18 hours after surgery (tachycardia) and increase in respiratory rate from 6 to 24 hours after surgery (tachypnea). In addition, a significant decrease in glucose of serum was observed. Bacterial culture was positive and peritoneal analysis of all rabbits in CLC group indicated the presence of bacteria and infection. Manuscript profile
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        48 - A fresh look at the latest treatment methods of complementary and regenerative medicine in sports horse injuries
        Amir Zakian Farshid Davoodi
        Nowadays, due to compression of sports competitions and the occurrence of more injuries, the role of sports medicine in minimizing the recovery and returning the animal to its previous performance with maximum power is more prominent than before. Various remedies are em More
        Nowadays, due to compression of sports competitions and the occurrence of more injuries, the role of sports medicine in minimizing the recovery and returning the animal to its previous performance with maximum power is more prominent than before. Various remedies are employed for these cases, but they are not accepted by all physician and veterinarian around the world. Complementary or alternative medicine should be considered as a type of treatment that is not in the medical world today or is not even registered, but some individuals and communities refer to it as the best treatment and define professional branches and sub-categories for it. But another unusual branch for treating diseases is regenerative or reconstructive medicine. In recent years, advances in cell biology, genetic immunology, and other fields have enabled regenerative medicine to fundamentally change health care. One of the duties of governmental and international organizations working in the field of health and treatment is to provide proper information and appropriate awareness of all fields of complementary and regenerative medicine for therapists and horse owners so that each person, after reviewing and consulting, can use these branches of medicine according to their needs and problems. Recently, significant progress has been made in the field of these two branches of unconventional medicine in European countries and North America Manuscript profile
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        49 - An overview of avian tendon and ligament problems
        Nikta  Moqadasi Abbas Raisi Hassan Norouzian
        Tendon is a mechanical bridge that transmits muscle strength to the bones and joints. Musculoskeletal disorders damages millions of dollars in economic losses each year to companies in the animal husbandry industry that inflict food. The tendon is mainly composed of ten More
        Tendon is a mechanical bridge that transmits muscle strength to the bones and joints. Musculoskeletal disorders damages millions of dollars in economic losses each year to companies in the animal husbandry industry that inflict food. The tendon is mainly composed of tenocyte and tenoblast cells and is oriented and organized by collagen fibers. Viral arthritis / tenosynovitis in poultry is one of the pathological manifestations of avian reovirus infection. Viral arthritis can be diagnosed by clinical observations and serological examination and radiological findings. Studies show the effect of vaccines on the prevention of this disease. Tendon mineralization in poultry can be a part of the natural process or can be caused by aging or tendon damage. Mineral deposition in tendons makes it a hard structure with less flexibility. The morphological properties of tissue and mineralized tendon cells have been studied. Several studies on the effects of activity on avian Gastrocnemius tendon have been performed. One of the tendon injuries is related to the patagial tendon, which responds well to treatment after surgery. The tendon plays a vital role in function of birds and is damaged, which causes irreparable problems. Therefore, it is necessary to know its structure and precise function in preventing damage as well as their more effective treatment. Manuscript profile
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        50 - Ligament injuries and their management in the hind limbs of dogs
        Ramin Mazaheri-Khameneh Mohammadmahdi Gooran Seyed Siavash Ghoreishi
        Ligament injuries are one of the most common injuries in small animals. These injuries can cause sudden pain, lameness and even weight intolerance. Early diagnosis and prompt treatment greatly increase the likelihood of successful treatment. Chronic injuries usually do More
        Ligament injuries are one of the most common injuries in small animals. These injuries can cause sudden pain, lameness and even weight intolerance. Early diagnosis and prompt treatment greatly increase the likelihood of successful treatment. Chronic injuries usually do not respond well to treatment and weaken the prognosis of treatment. Injury to the cruciate ligaments, followed by damage to the collateral ligaments, is one of the most common injuries to the knee joint. There are many ways to diagnose and confirm these injuries. These include ultrasonography and radiography. Numerous strategies for diagnosing and treating ligament injuries have been presented in previous studies, some of which have been attempted during this study. Manuscript profile
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        51 - Recent Advanced in Minimally Invasive Surgery; A Review on New Procedures and Instruments
        Mahdieh Katebian Mir Sepehr Pedram Mohammad Yasan Bangash mahbobeh abdi
        Minimally invasive surgeries are one of the most important revolutions in the history of surgery. recently, different methods of this type of surgery are widely used in medicine and veterinary medicine. With recent advances in minimally invasive surgery, a variety of su More
        Minimally invasive surgeries are one of the most important revolutions in the history of surgery. recently, different methods of this type of surgery are widely used in medicine and veterinary medicine. With recent advances in minimally invasive surgery, a variety of surgical methods have been introduced. Laparoscopic gallbladder resection is the most common type of minimally invasive surgery and many other surgeries have been introduced in the same way. This article introduces new methods in minimally invasive surgery. The further use of this type of surgery depends entirely on the development of new technologies in this field. The success of surgical procedures in the treatment of diseases is always measured by the amount of pain and trauma that the surgical method inflicts on the patient. Reducing these two factors has led to the progression and change surgical methods with minimal invasions in general and laparoscopic surgeries particularly in the last century. Manuscript profile
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        52 - Evaluation of effects of different cannulas and the initial incision size, on skin and underlying tissues in laparoscopic procedures in dog model.
        Mahdieh Katebian Mohamad Hejazi roja ebrahimi jalal rezaie hossein marjanmehr hossein asheq farnaz mahmoodzadegan hesam adin akbarein
        Objective- While many of studies have evaluated effects of trocar on incision characteristics non has taken the design of the cannula into consideration. This study was conducted to figure out the type of cannula design which is associated with a better healing at the i More
        Objective- While many of studies have evaluated effects of trocar on incision characteristics non has taken the design of the cannula into consideration. This study was conducted to figure out the type of cannula design which is associated with a better healing at the insertion site, and to investigate if the size of incision in the port site has an effect on the healing process. Procedure-6 trocars were inserted in each dog. five animals were used, allowing the total number of 10 insertions for 7 mm incisions and threaded cannula (group A), 10 insertions for 10 mm incision and threaded cannula (group B) and 10 for 10 mm incision and smooth cannula (Group C), which constituted 3 groups of study. Results-Macroscopic and Histopathology comparison between group A and group B revealed significantly higher degenerative changes and necrosis in the dermal and muscle layer and a higher loss of the peritoneal lining in group A than B. Hemorrhage in the dermal layer of the skin and acute inflammatory reaction was significantly higher in group B compared with C . Conclusions - This study showed that a smaller incision than the trocar’s external diameter has destructive effects on the tissues. Moreover, using a trocar with a threaded cannula can have harmful effects on the surrounding tissues and it is considered more destructive than a smooth cannula. Manuscript profile
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        53 - Local care of the hooves (Footbath application)
        Khosro Safari Nikroo mohammad ali sadeghi
        Foothbathes are one of the most efficient methods of control and prevention of foot lamenesses specially hoof infectious diseases in dairy herd facilities. In this article different types of foothbathes, design and structure, solutions and renewal rates have been review More
        Foothbathes are one of the most efficient methods of control and prevention of foot lamenesses specially hoof infectious diseases in dairy herd facilities. In this article different types of foothbathes, design and structure, solutions and renewal rates have been reviewed. Copper sulphate and formalin were the most frequently used solution and dimention of 81 cm of width, 3-3.7 m length and depth of 11 cm were introduced as standard dimentions. On the other hand due to environmental and human concerns these solution should be evacuated approperiatly. Also the most appropriate range of bath usage was between 1-4 times a day and 1-7 times a week and in each bath, between 100-300 cows can pass without significant reduction of chemical solution concentration. It should be noted that merely observing these instructions will not reduce digital diseases, and other health and disease control programs should be considered in the herd. Manuscript profile
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        54 - Gait biomechanics and digital growth and weight bearing pattern in dairy cows.
        mohammad ali sadeghi Khosro Safari Nikroo Mohammad mirhaj
        Lameness is one the most important problems in dairy herds and a major cause of financial loss and pain and discomfort to animals. Different surveys have revealed that most lameness causing lesions in cattle originate in the claw and in order to better understand the cl More
        Lameness is one the most important problems in dairy herds and a major cause of financial loss and pain and discomfort to animals. Different surveys have revealed that most lameness causing lesions in cattle originate in the claw and in order to better understand the claw disorders, one has to have good understanding of the anatomic structure, horn characteristics, and biomechanics of the claw. The claw is a direct product of the underlying living tissue and different factors affect the rate of horn growth and wear. Here, we aim to review the different factors effecting the horn growth and wear, weight bearing, and biomechanics of the claw. Manuscript profile
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        55 - Applied Anatomy and Histology of the bovine hooves and limbs
        Mohammad Mirhaj Mohammad Ali Sadeghi
        Bovine hoof with its fine structures and accurate function is used for routine locomotion. This part of common integument has special characteristics to carry on a very high resistance to external/internal stimuli. Production and components of different parts of this sm More
        Bovine hoof with its fine structures and accurate function is used for routine locomotion. This part of common integument has special characteristics to carry on a very high resistance to external/internal stimuli. Production and components of different parts of this small region vary and its variation in origin of production makes different protection against systemic disturbances or external/internal forces. Variation among species like cattle and horse limbs, expected performance (confinement and milk production versus athletic performance) and metabolic pressure on each animal results in different outcomes after hoof pathologies. For example, unlike horse, in cattle sinking of 3rd phalanx is more pronounced in the heel region. Horn capsule with its firm, sensitive and complex structure tries to neutralize the forces to which the limb is subjected. Any abnormality in hoof capsule vital tissues is a beginning for claw horn disruption lesion (CHDL) in a dairy farm. There are many hypotheses aiming to describe CHDL pathogenesis. No longer is it acceptable to believe that SARA = Subclinical laminitis. The disorder cannot be managed simply from a nutritional perspective and is Multifactorial. With better understanding of each part of this complex structure and the processes that occur after damage, a better understanding of the physiopathology of hoof capsule injuries is obtained. Manuscript profile
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        56 - Effect of Trace Mineral on the Hoof Health
        Fatemeh Kohansal Marzieh Faezi
        The claw quality is a product of claw shape, characteristics of the horn and anatomy of the inner structure. Hoof health is largely determined by the production of good quality horn of adequate resistance. The functional integrity of hoof horn essentially depends on a p More
        The claw quality is a product of claw shape, characteristics of the horn and anatomy of the inner structure. Hoof health is largely determined by the production of good quality horn of adequate resistance. The functional integrity of hoof horn essentially depends on a proper differentiation, i.e., keratinization of hoof epidermal cells. Keratinization of hoof epidermis is controlled and modulated by a variety of bioactive molecules and hormones. This process is dependent on an appropriate supply of nutrients including vitamins, minerals, and trace elements. Regulation and control of differentiation and nutrient flow to the epidermal cells play a central role in determining the quality and, consequently, the functional integrity of hoof horn. Decreasing nutrient supply to keratinizing epidermal cells leads to horn production of inferior quality and increased susceptibility to chemical, physical, or microbial damage from the environment. A growing body of evidence suggests that hormones, vitamins, minerals, and trace elements play critical roles in the normal development of claw horn and correct keratin formation. Increasing the bioavailability of trace minerals improves their utilization and thus contributes to an improved integrity of keratinized tissues. Manuscript profile
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        57 - A review of common instruments usage in cattle hoof trimming
        Ehsan Rostami Mojtaba Mohamaddoust Ahmadreza Mohamadnia
        Hoof trimming devices and facilities play an important role in hoof trimming, health of hoof trimmer and cow. Hoof trimming is a dangerous task for bot cows and trimmers and trimmer should consider usage of proper instruments and facilities for doing good job. Personal More
        Hoof trimming devices and facilities play an important role in hoof trimming, health of hoof trimmer and cow. Hoof trimming is a dangerous task for bot cows and trimmers and trimmer should consider usage of proper instruments and facilities for doing good job. Personal protections like usage of gloves, glass shields and trimming gown can help in improving health and security of the trimmer. In this current review hoof trimming devices like hoof scissors, hoof knives, sharpening of the hoof knives, angle grinders, hoof trimming discs were reviewed. Usage of angle grinders with proper disc may lower hazards for hoof trimmer and increase quality of hoof trimming and its final outcome. Manuscript profile
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        58 - Hoof blocks in dairy cows, fundamentals and techniques of application
        Mojtaba Mohamaddoust Fatemeh Kohansal Reyhane Sangtarash Ahmadreza Mohamadnia
        Digital lesions were treated by corrective hoof trimming, nonstroidal anti-inflammatory drugs and hoof blocks on a sound claw. Any claw lesions including sole ulcer, white line diseases, toe ulcer, digital wall lesions, penetrating interdigital necrobacillosis should b More
        Digital lesions were treated by corrective hoof trimming, nonstroidal anti-inflammatory drugs and hoof blocks on a sound claw. Any claw lesions including sole ulcer, white line diseases, toe ulcer, digital wall lesions, penetrating interdigital necrobacillosis should be treated using hoof blocks. Block height estimated as 25, width 50 and length 110 millimeters. Sound claw should be prepared for block adhesion with no eminence or any rugged part. The block should stick to the digit slightly toward the heel. Different glue and adhesives were used in hoof blocking. Functional glues generally divided in to two groups of Epoxy and Polyurethane. These glues are strong with good elasticity. Epoxy glues are synthetic glues consisting of two parts of resin and hardener and are stronger than polyurethane glues. Polyurethane glues are more tolerant than epoxies against rusting and trauma but because of Isocyanates are dangerous in use. Methymetacrylate adhesive glues are located between polyurethane and epoxy glues with strong and elastic features. Different techniques of hoof block usage were reviewed in this current study. Manuscript profile
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        59 - Cattle functional and corrective hoof trimming (Fundamentals and methods)
        Ahmadreza Mohamadnia
        Hoof trimming consider as one of daily activities in dairy farms, as cows refer to hoof trimming chute several times annually. Hoof trimming is a hard work that needs special facilities, knowledge and skills with continuing education to reach optimum efficiency in farms More
        Hoof trimming consider as one of daily activities in dairy farms, as cows refer to hoof trimming chute several times annually. Hoof trimming is a hard work that needs special facilities, knowledge and skills with continuing education to reach optimum efficiency in farms. Different hoof trimming techniques were used in past years and Dutch hoof trimming method published by Tussaint Raven consider as the first well explain method that still is the base of different hoof trimming methods around the world. However, White line reunion and Kansas methods also were used in different parts of the world. Hoof trimming were done in order to balance weight distribution between digits, transfer weight to normal digits and finding lesions in early stages. Corkscrew claws needs special trimming that were described in this article. Hoof trimming faults like over trimming of abaxial hoof wall, sole, heel and toe were mentioned in this article. Manuscript profile
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        60 - Hoof trimming as a part of lameness control in dairy farms
        Reyhane Sangtarash Marzieh Faezi
        Production diseases and conditions is common on intensive dairy farming which lead to pain and uncomforting or death in affected animals. Lameness has negative effects on comfort and economic issues. In many cases, lameness is associated with pain, which may change the More
        Production diseases and conditions is common on intensive dairy farming which lead to pain and uncomforting or death in affected animals. Lameness has negative effects on comfort and economic issues. In many cases, lameness is associated with pain, which may change the cow's motivation to perform certain behaviors (such as walking, lying, etc.) for pain reduction and discomfort. Reduced milk yield, poor reproductive performance, shortened productive time, increased culling risk and treatment costs are the major related economic losses. Despite all the negative effects of lameness on animals and the dairy industry, limited research has been done to evaluate preventive measures. Low awareness of lameness maybe the biggest problem in its detection and control. Lameness control strategies usually include hoof trimming and treatment of motility disorders. The aim of this study is to investigate the importance of hoof trimming and its effect on claw health (effect of hoof trimming on infectious diseases, non-infectious diseases or other claw-related injuries), behavioral variables (lying time and locomotion score), physiological variables (heart rate, respiration rate, plasma cortisol level, etc.), production variables (milk production and reproduction) and other factors related to hoof trimming. Manuscript profile
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        61 - A review on hoof trimming timing in cows
        Marzieh Faezi Alireza Bahonar Ahmadreza Mohamadnia
        Hoof trimming as a part of hoof health management is one of the important parts of herd health management system. Timing of hoof trimming and its method are the main subjects that must be known for an efficient hoof trimming program. In the current study, the different More
        Hoof trimming as a part of hoof health management is one of the important parts of herd health management system. Timing of hoof trimming and its method are the main subjects that must be known for an efficient hoof trimming program. In the current study, the different suggested timings of trimming (around drying, early, middle and end of lactation) have been reviewed. Although the need for more research to find the best time for hoof trimming is yet necessary, an appropriate timing is suggested based on the current literature. Also the unique role of accurate data recording system in time management of trimming is mentioned. Manuscript profile
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        62 - Resuscitation and Critical Care of Neonatal Calves
        faeze vaghar seyedin nima farzaneh
        The perinatal¬ period is the most perilous in the life of all animals. Perinatal calf mortality in the first 48 hours of life has been estimated to be between 3 and 10.3%. More than 60% of producers have reported¬ that most of their calf mortality occurs at birth. The m More
        The perinatal¬ period is the most perilous in the life of all animals. Perinatal calf mortality in the first 48 hours of life has been estimated to be between 3 and 10.3%. More than 60% of producers have reported¬ that most of their calf mortality occurs at birth. The main causes of perinatal morbidity and mortality are¬, in descending order of importance¬, combined respiratory and metabolic acidosis¬, parturient trauma, hypoglobulinemia, congenital infections and deficiencies, and omphalophlebitis. Some¬ 90% of calves that die in the perinatal period were alive¬ at the start of calving, and so much of this loss is preventable. Management of the newborn¬ dairy calf is best achieved through implementation of simple protocols that document¬ the correct strategies to be followed at the herd level and the correct procedures to be performed¬ at the individual animal level. These protocols cover management of the prepartum cow, management of calving (monitoring of eutocia and detection and management¬ of dystocia)¬, and newborn calf care. Therefore, it is imperative to provide immediate evaluation and care of newborn calves to ensure calf survival and health and prevent economic losses¬ associated with perinatal¬ mortality. Manuscript profile
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        63 - Cesarean section procedure in cattle
        Khosro Safari Nikroo Negin Rahimdoust Mozhdehi Samaneh Ghasemi
        Cesarean operation is one of the oldest surgical procedures in veterinary medicine. In farm animals practice, especially in meat producing animals, this technique is a relatively frequent and performed when normal parturition is not possible. Dystocia is the most import More
        Cesarean operation is one of the oldest surgical procedures in veterinary medicine. In farm animals practice, especially in meat producing animals, this technique is a relatively frequent and performed when normal parturition is not possible. Dystocia is the most important reason for cesarean procedure and survival of the cow and the calf, and maintenance of fertility are the main aims of cesarean in cattle. In this article, the history of this technique has been briefly mentioned and the aim of this article is to describe the indications of cesarean, decision making for surgery, preparaton of the patient, different cesarian surgical approaches, as well as post-operative cares and complications in cattle. Manuscript profile
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        64 - Prevalence, causes, risk factors, prevention strategies and treatment of dystocia in dairy cattle
        Niloufar Tashakkori nima farzaneh
        Each case of dystocia is a clinical problem that may be solved if a correct procedure is followed. The diagnosis and treatment of dystocia requires a good understanding of normal parturition and sensitivity to the welfare of both dam and offspring. Difficult birth will More
        Each case of dystocia is a clinical problem that may be solved if a correct procedure is followed. The diagnosis and treatment of dystocia requires a good understanding of normal parturition and sensitivity to the welfare of both dam and offspring. Difficult birth will occur when the expulsive forces are insufficient, when the birth canal is of inadequate size and shape, or when the presenting diameter of the fetus is unable to pass through the normal birth canal because it is too large or its disposition prevents it from doing so. The incidence of dystocia in heifers has been calculated to be anywhere from three to ten times that of multiparous cows, whether in beef or dairy cattle. Risk factors for dystocia are fetal-dam disparity, abnormal fetal position, vulval, vaginal, or cervical stenosis and uterine torsion. Preventing dystocia, particularly in first-calf heifers, is a very important component of a successful reproductive program on any dairy or beef operation and there are numerous factors have been involved in the incidence of dystocia. Even when plans are in place to limit dystocia risk to an acceptable level (<15% for heifers, <5% for cows), there are still cases of dystocia in beef and dairy herds. One of the most important fundamentals for optimum dystocia management is for the owner to know when to intervene or call for assistance. Manuscript profile
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        65 - Maternal Dystocia: Causes and treatment
        Niloufar Tashakkori nima farzaneh
        Maternal dystocia includes defects of the birth canal and defects of the expulsive forces. Defects of the birth canal would be due to the pelvic constriction, failure of cervical dilation, incomplete relaxation of the caudal vagina and vulva and other physical abnormali More
        Maternal dystocia includes defects of the birth canal and defects of the expulsive forces. Defects of the birth canal would be due to the pelvic constriction, failure of cervical dilation, incomplete relaxation of the caudal vagina and vulva and other physical abnormalities causing obstruction such as remnants of the paramesonephric ducts. The expulsive force of labour is due to a combination of myometrial contractions and straining induced by the contraction of the abdominal muscles with a closed glottis. Because the abdominal muscles do not come into play until the myometrium has forced the fetus and fetal membranes into the pelvic canal and stimulated the pelvic sensory nerve receptors, it is logical to consider first the expulsive deficiencies that may arise in the myometrium. These may occur spontaneously or dependently and are called, respectively, primary and secondary uterine inertia. Manuscript profile
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        66 - Fetal dystocia 1. Obstetrical maneuvers; Dystocia due to postural defects; Dystocia due to faulty position
        Niloufar Tashakkori nima farzaneh
        The aim of manipulative procedures in the monotocous species must always be to ensure that the fetus is in normal disposition before attempting delivery. Correction of defects of presentation, position, and posture can be achieved only by intrauterine manipulation of th More
        The aim of manipulative procedures in the monotocous species must always be to ensure that the fetus is in normal disposition before attempting delivery. Correction of defects of presentation, position, and posture can be achieved only by intrauterine manipulation of the fetus. Retropulsion of the fetus into the uterus is essential for repositioning it. After diagnosing the cause of dystocia and deciding on a plan of action, the obstetrician should consider whether the available facilities are appropriate, and whether the equipment is adequate to carry out the treatment successfully. In severe forms of dystocia, the veterinarian should always seek the assistance of a professional colleague and consider whether it might be appropriate to transport the animal to a place with hospital facilities, provided that the animal is in a fit state to travel. Obstetrical manipulation per vaginam should be performed as cleanly as possible. It is impossible to perform them aseptically because there will inevitably be some contamination. Manuscript profile
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        67 - Fetal Dystocia 2. Dystocia Due to Faults of Presentation, Dystocia Due to Twins, Dystocia Due to Fetomaternal Disproportion
        Saghar Alizadeh Ghamsari Niloufar Tashakkori nima farzaneh
        The aim of manipulative procedures in the monotocous species must always be to ensure that the fetus is in normal disposition before attempting delivery. Correction of defects of presentation, position, and posture can be achieved only by intrauterine manipulation of th More
        The aim of manipulative procedures in the monotocous species must always be to ensure that the fetus is in normal disposition before attempting delivery. Correction of defects of presentation, position, and posture can be achieved only by intrauterine manipulation of the fetus. Retropulsion of the fetus into the uterus is essential for repositioning it. After diagnosing the cause of dystocia and deciding on a plan of action, the obstetrician should consider whether the available facilities are appropriate, and whether the equipment is adequate to carry out the treatment successfully. In severe forms of dystocia, the veterinarian should always seek the assistance of a professional colleague and consider whether it might be appropriate to transport the animal to a place with hospital facilities, provided that the animal is in a fit state to travel. Obstetrical manipulation per vaginam should be performed as cleanly as possible. It is impossible to perform them aseptically because there will inevitably be some contamination. Manuscript profile
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        68 - Management of birth canal injuries in dairy cows
        Bahare Hafezi mohammad ali sadeghi Ahmadreza  Mohammadnia
        Injuries of the birth canal in cows (perineal lacerations, fistula…) cause significant economic loss in dairy herds. These injuries usually are associated with obstetric trauma during labor. Third degree perineal lacerations and fistula formation usually happen because More
        Injuries of the birth canal in cows (perineal lacerations, fistula…) cause significant economic loss in dairy herds. These injuries usually are associated with obstetric trauma during labor. Third degree perineal lacerations and fistula formation usually happen because of dystocia, improper repairs, abscesses and forced extractions and lead to fecal contamination of the birth canal and reduced fertility. The main reason for the birth canal and external part of the reproductive tract surgery is to restore fertility of the animal and repair the injuries associated with dystocia. In this review the causes, management, and treatment of these disorders by emphasizing on the importance of birth canal injuries in cows were discussed. Manuscript profile
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        69 - Septic arthritis in cattle and calf
        Seyed Mousa Mousavi Samaneh Ghasemi
        Septic arthritis is an important cause of lameness in cattle and calves and delay in treatment, can lead to early culling, a decrease in production, and economic losses in herd. Although responsible for septic arthritis but can also be caused by other microorganisms. Th More
        Septic arthritis is an important cause of lameness in cattle and calves and delay in treatment, can lead to early culling, a decrease in production, and economic losses in herd. Although responsible for septic arthritis but can also be caused by other microorganisms. This condition occurs when joint space affects by invasion of various microorganisms. Failure of transfer of passive immunity, penetrating wounds, septicemia, and therapeutic or diagnostic interventions are the causes of septic arthritis. Lameness, joint effusion, pain, and fever are the most important of clinical signs of septic arthritis. One or more joints may be affected. Complete physical examination, synovial fluid and blood analysis, and imaging studies techniques are used as diagnostic tools for septic arthritis. Early diagnosis and appropriate treatment of septic arthritis are necessary to improve prognosis. Treatment strategy of septic arthritis includes antimicrobial therapy, anti-inflammatories, and joint lavage. Pathophysiology, diagnosis and treatment of septic arthritis are described in this article. Manuscript profile
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        70 - Flexural and Angular deformity in the Calves
        hamid reza moslemi navid Ehsan pour
        As the anatomical condition of the limbs is extremely important for production performance, animal welfare, as well as economic consequences, it is very important to study the types of limbs malformations in infants and provide corrective measures. A congenital malforma More
        As the anatomical condition of the limbs is extremely important for production performance, animal welfare, as well as economic consequences, it is very important to study the types of limbs malformations in infants and provide corrective measures. A congenital malformation of the animal's limbs is more common in calves, lambs, and foals, involving flexor and extensor tendons in the fetlock and pastern joints. Deformities of the wrist and palmar-carpal joint in the forelimbs are the most common congenital deformities in calves. A non-surgical treatment is performed in cases whose limbs can be opened with the hand, and the ventral part of the fingers is in contact with the ground. The use of surgical treatment is mainly reserved for severe cases of deformity and calves with insufficient correction after splints and casts have failed. Generally, calves with flexion deformity have a good prognosis. Angular deformity of the limb refers to the deviation of the limb outward (valgus) or inward (varus). An Dorso-Palmar (Plantar) position is necessary to examine and measure the deformity's anatomical position. Angular deformities associated with abnormal bone growth plates can be corrected by removing the bone matrix or delaying on growth plate using of fixation through the growth plate. Furthermore, there are two other surgical methods for correcting angular deformity: osteotomy using the closing wedge and the step-wise method. Angular deformities related to imbalances in growth plates have a good prognosis. Secondary angular deformity caused by orthopedic injuries in the opposite limb has a poor prognosis. Manuscript profile
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        71 - Local anethetic techniques of distal limbs in cattle
        mohammad ali sadeghi Samaneh Ghasemi
        Cattle usually tolerate physical restraint so, many surgical or therapeutic techniques including limbs procedures can be performed by using a combination of mild sedation and local or reginal anesthesia. These techniques avoid the risk of general anesthetic and are rela More
        Cattle usually tolerate physical restraint so, many surgical or therapeutic techniques including limbs procedures can be performed by using a combination of mild sedation and local or reginal anesthesia. These techniques avoid the risk of general anesthetic and are relatively simple and inexpensive with low side effects. Local or reginal anesthesia involve the local anesthetic drug that provide the absence of sensation in a region of body. Use of appropriate of local anesthesia is an important tool to perform different therapeutic and surgical procedures in limbs of cattle. It is important that local anesthesia provides sufficient analgesia for pain management. Lidocaine is the most common local anesthetic drug used in cattle. Before injection, the skin should be cleaned to reduce the chance of introducing pathogens. There are several techniques of local and reginal anesthesia including nerve block, ring block, four-point and, intravenous regional anesthesia for distal limbs in cattle. In nerve block, an anesthetic drug injects near specific nerves while ring block performs by injection of an anesthetic drug circumferentially around the mid-metacarpus or metacarpus region. In low four-point block, local anesthetic drug is injected in four sites to anesthetize the lower limb from pastern distally. During intravenous regional anesthesia, an anesthetic drug is intravenously injected by a catheter followed by the placement of a tourniquet around the limb. Consideration to the volume of used local anesthetic drug is necessary for prevention of toxic effect of these drugs. In this article, the most common local anesthetic techniques of the distal limbs in cattle are described. Manuscript profile
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        72 - Acquried tendon injuries in cattle
        Zahra Sadat  Yousef Sani Ahad Jafari Rahbar Alizadeh Samaneh Ghasemi
        Tendon disorders are the important cause of lameness, decreased production and loss of economic in cattle. These disorders may be congenital or acquired. Acquired tendon injuries involve tendon laceration, avulsion and rupture. Direct trauma, breeding injuries, bulls f More
        Tendon disorders are the important cause of lameness, decreased production and loss of economic in cattle. These disorders may be congenital or acquired. Acquired tendon injuries involve tendon laceration, avulsion and rupture. Direct trauma, breeding injuries, bulls fight, and, handling accidents are the most causes of tendon injuries in cattle. Deep and superficial digital flexor tendons and gastrocnemius tendon are commonly affected. Clinical signs of tendon injuries depend on the severity of injury. Pain, mild to severe lameness and recumbency are the clinical signs associated with tendon injuries in cattle. Treatment of tendon injuries consist of stall confinement, anti-inflammatory medications, limb supporting through application of cast or splint and tenorrhaphy. The prognosis of tendon injuries affects by the severity of injury. Common acquired tendon injuries in cattle are described in this article. Manuscript profile
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        73 - Digit amputation in cattle
        Sajjad  Pishbin Farzad Hayati
        Lameness of limbs is one of the most important problems of today's cattle farms, which causes irreparable economic losses, so that about 60% of cows in each herd are lame at least once a year (finger injuries in Iran are 31.8%). Injuries of the digits is one of the majo More
        Lameness of limbs is one of the most important problems of today's cattle farms, which causes irreparable economic losses, so that about 60% of cows in each herd are lame at least once a year (finger injuries in Iran are 31.8%). Injuries of the digits is one of the major causes of lameness in cattle. Bones of the digits in cattle include the first, second and, third phalanx. Two vestigial digits are existed in cattle. The medial digit and the lateral digit are the main weight bearing structures on the forelimb and hindlimb, respectively. One of the practical treatments for injuries of the digits is its amputation. Among the most important causes of digit amputation, can mention osteomyelitis of finger and navicular bones, septic arthritis of interdigital joints, fractures and hoof traumas that have not responded to other conservative treatment. Most of digit amputation procedures perform under local anesthetic techniques with the cattle standing position. Selection of digit amputation techniques depends on several factors, such as the lesion type and the extent of involved anatomical structures. The most common surgical method is to amputate the digit through the distal aspect of the proximal phalanx without the need for a skin flap, which usually has a good prognosis and is effective in improving the economic life of the animal. Todays, limb amputation and the use of prosthesis are indicated in cattle or calf with untreatable musculoskeletal trauma or infection. General anesthesia is recommended for limb amputation. Although the short-term prognosis for limb amputation is good, the long-term prognosis depends on the weight of the animal and caring condition. Manuscript profile
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        74 - Management of fractures in cattle
        Nasim Qaemifar Faezeh Alipour
        Today, bone fracture is one of the common problems that can occur in animals and can cause many damages. Fracture is common in ruminants including cattle, these animals are generally considered as good candidates to perform surgical operations in order to correct fractu More
        Today, bone fracture is one of the common problems that can occur in animals and can cause many damages. Fracture is common in ruminants including cattle, these animals are generally considered as good candidates to perform surgical operations in order to correct fracture and recovery. Generally, fractures which occur in ruminants and generally in large ruminants are of great importance for treatment because according to experiences, despite the cost incurred, the treatment of these complications is a good result .Often fractures occur in hind limb and fore limb parts of the animals and fewer cases are reported from the other parts. Selection of appropriate treatment method and control of these complications is affected by several factors, but in general, economic factors in patients can be considered as one of the most effective factors in this selection. About fracture management, some factors such as physical examination, prevention of subsequent secondary infection and etc, are discussed. In general, from 1950 onwards, the use of internal fixation in the treatment of fractures increased. The costs that are used to provide internal fixation instruments, preparation of radiographs, the salary of surgeons, postoperative cares and etc, may be considered for the owner, therefore, it should be considered before the beginning of surgery. Although there are many studies about the modification of fractures with external fixation, but there is a little data about the use of this system in large animals. In this article, the principles of treatment of internal and external fixation fractures are mentioned. Manuscript profile
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        75 - Ligamentous injuries of the stifle joint in cattle
        Zahra Sadat  Yousef Sani Ahad Jafari Rahbar Alizadeh mohammad ali sadeghi
        Lameness of the hindlimbs originating from the stifle joint is one of the causes of pain, production losses, and culling from herd in cattle. Stifle is a large joint divided into femeropatellar and lateral and medial femorotibial joints. The major soft tissue structures More
        Lameness of the hindlimbs originating from the stifle joint is one of the causes of pain, production losses, and culling from herd in cattle. Stifle is a large joint divided into femeropatellar and lateral and medial femorotibial joints. The major soft tissue structures of the stifle joint are lateral and medial collateral ligaments, cranial and caudal cruciate ligaments, lateral, middle, and medial patellar ligaments, and menisci That contribute to stabilize the stifle joint and its function. Different disorders including fractures, arthritis, and injuries of the menisci, collateral, and cruciate ligaments, and upward fixation of the patella affect stifle joint in cattle. The most important sequela of the stifle injuries is degenerative joint disease. Various degree of joint effusion, pain and lameness are the common clinical signs of stifle injuries in cattle. Lameness of the stifle joint may be difficult to diagnose and treat. Therefore, careful examination of the hindlimb is indicated. Radiography and ultrasonography can be used for diagnosis of stifle joint injuries in cattle. Because of the economic considerations and other limitations, advanced diagnostic techniques such as arthroscopy, computed tomography, and magnetic resonance imaging are uncommonly performed in cattle. Conservative management and surgical techniques are used for treatment of stifle disorders in cattle. Economic value of the cattle, severity of injury, presence of degenerative joint disease, availability of surgical equipment, and expertise of the surgeon should be considered for selecting of treatment options. Prognosis of stifle disorders in cattle is variable and depends on the type of injury, its severity, involved structures and concurrent injuries as well as cattle condition. In this article the most important soft tissues injuries of the stifle joint, clinical signs, diagnosis, treatment and prognosis of these injuries are described. Manuscript profile
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        76 - An update to treatment of canine atopic dermatitis
        Javad Khoshnegah
        Atopic dermatitis is a common pruritic and inflammatory dermatosis with genetic background and specific clinical manifestations. The present study was carried out with the aim of improving the knowledge and integration of the treatment protocols of veterinarians in Iran More
        Atopic dermatitis is a common pruritic and inflammatory dermatosis with genetic background and specific clinical manifestations. The present study was carried out with the aim of improving the knowledge and integration of the treatment protocols of veterinarians in Iran. The current research is a review based on the based on the task force for the treatment of canine atopic dermatitis (International Committee of Allergic Diseases of Animals) and a summary of the author's researches in the field of dermatology. The treatment of acute flares of canine atopic dermatitis should involve three parts; 1- To search for and then to eliminate the causes and/or aggravating allergens such as plant pollen allergens, house dust mites (dermatophagoides), pyoderma and/or Malassezia dermatitis. 2- Antimicrobial treatment and improvement of skin and hair health, such as bathing with mild shampoos. 3- To control pruritus and skin lesions with interventions that include topical and oral glucocorticoids, oral Oclacitinib, and injectable recombinant interferons. 4- Immunotherapy using specific allergens and prophylactic administration of topical glucocorticoids are the only interventions that may prevent or delay the recurrence of dermatitis. There is no conclusive evidence to prove the efficacy of: 1- Antihistamines in the treatment of atopic dermatitis in dogs 2- Administration of oral essential fatty acids due to the long time required for any effective effect. The treatment of acute flares of atopic dermatitis is multifaceted, and in order to achieve the optimal therapeutic effect, therapeutic interventions must be combined. Before designing a treatment plan, it is necessary to consider the quality of life of dogs and their owners, as well as the preference of the owner's opinion. Manuscript profile
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        77 - patellar luxation in dogs
        Alireza Shaikhzadeh Amin Bigham-Sadegh
        Patellar luxation is a common orthopedic problem in dogs. Both large and small breed dogs may be affected; the disease may be seen in cats as well. Medial luxation is more common than lateral luxation and is usually diagnosed in dogs of small breed. patellar luxation ba More
        Patellar luxation is a common orthopedic problem in dogs. Both large and small breed dogs may be affected; the disease may be seen in cats as well. Medial luxation is more common than lateral luxation and is usually diagnosed in dogs of small breed. patellar luxation based on severity of occurred changes divided to 4 different grades. Patellar luxation is a congenital/developmental disorder, but it could be secondary to traumatic accident causing tearing or stretching of the joint capsule and fascia, leading to femoropatellar instability. Diagnosis is based on clinical evidence of patellar instability; however, diagnostic imaging is required to assess the amount of skeletal deformity and then the most appropriate method of treatment. Clinical signs of dogs with patellar luxation can vary from animal to animal and are only partially related to the degree of concomitant skeletal deformities. Lameness may be intermittent or continuous, and usually is a mild-to-moderate weight bearing lameness with occasional lifting of the limb. Concurrent rupture of the CrCL has been reported in a study in 41% of the stifle joints of dogs with medial patellar luxation. Surgical options include both soft tissue and osseous techniques, however, in most of the cases, a combination of more procedures is used to achieve the correction of the luxation. Complication rate is generally low and the most common complications include reluxation and implant-associated complications. Prognosis is generally favorable, with most of the dogs returning to normal limb function. This article describes patellar luxation features in dogs, including clinical presentation, diagnosis, and treatment options available Manuscript profile
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        78 - a review on on Juvenile Orthopedic disease in dogs and cats
        Aref Ghashghaee Amin Bigham-Sadegh
        Orthopedic diseases of young animals affect the musculoskeletal system of juveniles, and most of these diseases can be traced to pathological processes (such as diseases, toxins, improper nutrition, trauma) during this period. These diseases related to bones and joints More
        Orthopedic diseases of young animals affect the musculoskeletal system of juveniles, and most of these diseases can be traced to pathological processes (such as diseases, toxins, improper nutrition, trauma) during this period. These diseases related to bones and joints begin and develop during skeletal development after birth, in the first 26 weeks of life. This group of pathological conditions of young dogs and cats, including congenital and neonatal orthopedic diseases, includes diseases that occur in the prenatal period or in the first 3 to 4 weeks of life. During the growth period, the morphology of the joints develops, the bones also mature and reach their length and shape in an adult animal. Orthopedic diseases of young animals are deviations of these regular processes. These diseases are a common problem in dogs and cats, can be painful and are not easily noticeable. These diseases can affect the bones, cartilage and joints of young animals and cause lameness, stiffness and difficulty moving. Early diagnosis and treatment are very important for successful outcome in these diseases. Veterinary clinicians should be aware of the signs and symptoms of these diseases, including lameness, joint pain, swelling, and difficulty moving. Diagnostic tests such as radiography and blood tests can help make the diagnosis. According to the type of disease, the treatment options are different and can include drugs, surgery or other interventions and may even be incurable. Prevention is also important in reducing the risk of orthopedic diseases in young dogs and cats, by preventing the mating and sterilization of animals with genetic disorders, it is possible to prevent the next generation from getting genetic diseases. Nutrition, exercise and weight management can also contribute to healthy bone and body growth in young animals. Veterinary course checkups can also help identify potential problems at the right time and prompt interventions and treatment. Manuscript profile
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        79 - A Review of Structure and Mechanisms of Tendon Injury and Repair in Small Animals
        Fatemeh Iraji Aboutorab  Tabatabaei Naeini
        Tendons are soft connective tissues composed of parallel collagen fibers embedded in an extracellular matrix. This organized structure allows the tendons to bear and transfer large forces between the muscle and the bone. Tendons contain 86% collagen, 1-5% proteoglycan , More
        Tendons are soft connective tissues composed of parallel collagen fibers embedded in an extracellular matrix. This organized structure allows the tendons to bear and transfer large forces between the muscle and the bone. Tendons contain 86% collagen, 1-5% proteoglycan ,and 2% elastin, which are calculated as dry weight, and water is responsible for 60-80% of the wet weight of the whole tendon. Tendon healing can be generally divided into 3 phases; the repair, inflammation, and remodeling phases. Although the tensile strength of the healed tendon improves over time, it does not reach the level of uninjured tissue. Manuscript profile
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        80 - the cartilage and cartilage healing in dogs and cats
        iman farhangnia
        Cartilage is a strong, flexible connective tissue that protects joints and bones. It acts as a shock absorber throughout body. Cartilage is divided into different types based on the type of fibers in the underlying tissue as well as the percentage of their composition, More
        Cartilage is a strong, flexible connective tissue that protects joints and bones. It acts as a shock absorber throughout body. Cartilage is divided into different types based on the type of fibers in the underlying tissue as well as the percentage of their composition, each has different functional characteristics. Hyaline cartilage is the most common and abundant type of cartilage rich in type ΙΙ of collagen fibers and proteoglycan. Elastic cartilage has more flexibility and in the matrix of this cartilage, in addition to the type ΙΙ of collagen fibers, a large amount of elastic fibers is also present. In fact, the presence of these elastic fibers is a factor in the ability of this type of cartilage to change shape and return to its original state. The fibrocartilage is the strongest type of cartilage. The characteristic feature of this type of cartilage is high weight bearing. Fibrocartilage contains collagen fibers scattered between layers of the matrix. The restorative strength of cartilage tissue is very limited and the repair of this tissue after injury is always accompanied by challenges and problems. Articular cartilage damage is considered as one of the most important challenges of orthopedic surgeons. Today, different methods are used to treat the articular cartilage defect, however, in none of the methods complete restoration and restoration of tissue integrity of articular cartilage is achieved. Surgical procedures are divided into two categories, reparative and restorative surgery. The purpose of this article is to review the structure of cartilage and the methods of articular cartilage healing. Manuscript profile
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        81 - External Skeletal Fixators in Small Animal
        hamid reza moslemi navid Ehsani pour Faeze  Emarloo
        An external skeletal fixator is an orthopedic method for treating open or closed fractures of long tubular bones, joint stiffness, bone lengthening, and congenital malformations. An external skeletal fixator is a device that is installed outside the organ and inserts p More
        An external skeletal fixator is an orthopedic method for treating open or closed fractures of long tubular bones, joint stiffness, bone lengthening, and congenital malformations. An external skeletal fixator is a device that is installed outside the organ and inserts pins into the fracture to fix it and adjust the position of the pin. They are connected to the frame and secured with bolts and nuts. Fixtures have changed significantly in appearance and biomechanics over time, but the principle and function remain the same. These fixtures consist of pins or thin stainless steel wires that penetrate the skin and reach the bone. This way the broken part is fixed in the right direction. Depending on the body geometry and shape, these external skeletal fixators are available in different types such as linear, circular, and hybrid fixators. The simplest and most common type of external skeletal fixator is the linear fixator. The use of an external fixator has several advantages over other fixation methods such as stabilization of the fracture at some distance from the injury site, no need for a cast, ease of patient movement, and minimal involvement of the joint. Premature loosening of the pin is the most common complication causing pain, inflammation, and discharge from the pin tract. Although these fixators are versatile and effective treatment models, they require careful maintenance during treatment. Before deciding to use an external fixator, the patient's and pet's owner's ability to comply with postoperative care instructions should be considered. This article reviews the types of external fixators, postoperative care, and their complications. Manuscript profile
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        82 - A review on external coaptation methods in small animal
        pouriya almasi Aboutorab  Tabatabaei Naeini
        External fixation by means of coaptation means using casts, splints, bandages, and slings to immobilize the injured limb. These methods if used properly approximate the shape of the limb on which they are applied and provide stable fixation of bone fragments without the More
        External fixation by means of coaptation means using casts, splints, bandages, and slings to immobilize the injured limb. These methods if used properly approximate the shape of the limb on which they are applied and provide stable fixation of bone fragments without the need for surgical implants at the fracture site. External fixation of orthopedic injuries in veterinary medicine has significant advantages over open fixation and internal fixation. In most cases, the soft tissue and vascular damages, the risk of infection, and the cost of its use can be much lower than surgical intervention. Careful case selection is required to achieve successful treatment of fractures with external coaptation. Temporary fixation methods are usually used to prevent edema, relieve pain, reduce subsequent soft tissue damage, protect the wound from further contamination, prevent the conversion of closed fractures to open fractures, and stabilize the fractured particles in acutely injured animals. Various types of External coaptations are available in veterinary practice to provide the best external fixation of injuries. Therefore, it is essential for the practitioners in this field to have sufficient familiarity with different methods and their uses. As a general rule, external coaptation is an acceptable mode of fracture repair for animals that are younger than 1 year of age, because they heal faster. External coaptation best neutralizes flexion forces on distal fractures and requires stabilization of the joint above and below the fractured site. Therefore, coaptation has the disadvantage of prolonged immobilization of the limb, which can cause severe atrophy from "disuse atrophy" and possible "fracture disease". Manuscript profile
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        83 - Orthopedic examination of the hind limb in small animal
        hamid reza moslemi Mahshid Farmand
        Lameness is a common complaint in small animal medicine. Orthopedic examination is performed by visual and manual assessment of the patient. In most cases, the affected extremity is identified, but the exact origin of that extremity remains obscure and sometimes difficu More
        Lameness is a common complaint in small animal medicine. Orthopedic examination is performed by visual and manual assessment of the patient. In most cases, the affected extremity is identified, but the exact origin of that extremity remains obscure and sometimes difficult. Orthopedic examination plays an important role in determining the location of lameness, diagnosing its cause, and finding appropriate treatment. Early diagnosis of musculoskeletal problems is very important to apply appropriate treatment and preventive measures in the early stages of disease progression. Patients presenting with symptoms of musculoskeletal abnormalities should undergo a complete orthopedic examination. A systematic approach to orthopedic examination is important to assess all structures and ensure that no part is missed. The purpose of orthopedic examination is to assess the presence or absence of the disease in the patient and determine the causes of its occurrence. The orthopedic examination includes history taking, walking observation, step analysis and evaluation, and clinical examination of the patient. A history of lameness, previous diagnoses and treatments and their effects, the presence of other systemic diseases, and diet should be documented before the initiation of clinical examination. The time of onset of lameness, possible causes, and the timing of progression also help in a better diagnosis. It is very important to observe the patient walking from different directions at different speeds. Observing the patient going up and down stairs and ramps may also help. Understanding movement and gait is important for diagnosing many musculoskeletal and neurological problems. Gait analysis should be performed before any orthopedic or neurological examination. Gait analysis can help further clarify which limb is affected. Finally, an orthopedic clinical examination of the animal is performed. This article describes methods for clinical examination of the hind limb. Manuscript profile
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        84 - Internal Fixation Methods of Bone Fractures in Small Animals
        Arian Pouramin Seifollah  Dehghani
        Bone fractures in dogs and cats are usually see and we concern with those in the clinic. Usually, fractures occur after a traumatic accident such as being hit by a car or falling from a height, some fractures occur following pathological bone weakening, which is seen wi More
        Bone fractures in dogs and cats are usually see and we concern with those in the clinic. Usually, fractures occur after a traumatic accident such as being hit by a car or falling from a height, some fractures occur following pathological bone weakening, which is seen with some neoplastic conditions such as osteosarcoma. The main goals of fracture stabilization; Immobilization of broken parts, quick repair of the damaged bone, return of primary mobility, full function and stability to weight bearing of the bruise limb. All internal and external fixation methods that allow significant intersegmental motion under weight bearing are considered flexible fixation. The best important point in the stabilization of fractures is that a possibility of repair, that is, the blood supply to the place is maintained and the fixation is not so tight that it leads to a delay in bone fusion. Open fixation and internal fixation have been used to restore bone anatomy and original mobility and to overcome the limitations encountered when treating fractures with skeletal traction or cast immobilization. The main goal of internal fixation is to achieve rapid and, if possible, full function of the affected limb with rapid rehabilitation of the patient. The selection of the internal fixation method is based on the classification of the fracture, break bone, synchronize injuries, open fracture, and of course the forces that are neutralized by the fixation method. Internal stabilization implants are made of stainless steel and include; There are intramedullary pins, orthopedic wire, plates and screws. Manuscript profile
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        85 - Orthopedics examination of the fore limb in small animal
        hamid reza moslemi navid Ehsani pour Faeze  Emarloo
        ameness is a common problem in small animal medicine. Since animals, especially dogs, bear most of their weight on their front legs, it seems necessary to examine the fore limb. Diagnosis and treatment of fore limb lameness are often difficult. Diagnosis of the lesion i More
        ameness is a common problem in small animal medicine. Since animals, especially dogs, bear most of their weight on their front legs, it seems necessary to examine the fore limb. Diagnosis and treatment of fore limb lameness are often difficult. Diagnosis of the lesion is difficult because patients usually do not show obvious pain on palpation. Investigation of the cause of lameness and the anatomical location of the lesion depends on the age, breed, and lifestyle of the animal. Therefore, a systematic orthopedic examination of the extremity is critical to ensure that all structures are assessed and no part is overlooked. An orthopedic examination includes not only a clinical examination of the patient but also an anamnesis, gait observation, stride analysis, and evaluation. First, a history of lameness, diagnosis, previous treatment, and its effectiveness, presence of other systemic conditions, and diet should be evaluated. Assessing a patient's gait on flat and sloping surfaces at different speeds can help understand which limb is lame. Studying and analyzing animal movements is considered a very important step in detecting organ damage and abnormalities. Abnormal gait that may be caused by nerve or musculoskeletal damage is therefore called lameness. It is caused by hereditary, congenital, developmental disorders, trauma, and infection of this organ. Finally, an orthopedic clinical examination of the animal is performed. The appearance of pain during the examination indicates the localization of the lesion since an orthopedic examination of the organ does not cause pain in healthy animals. First, the normal, seemingly healthy side is checked so that the animal is calm and so that individual responses to specific tests can be judged. Therefore, this article describes a method for systematic orthopedic examination of the fore limb. Manuscript profile
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        86 - The healing process of bone lesions and fractures, effective treatment methods
        Haniyeh yabandeh jahromi Abodol hamid Meymandi Parizi Alireza Shaikhzadeh
        Fracture repair involves proliferation and differentiation of multiple tissue types in a sequence followed by regeneration. All of these processes may be affected by medications. Some drugs can affect the proliferation of primary callus tissue, others can affect the dif More
        Fracture repair involves proliferation and differentiation of multiple tissue types in a sequence followed by regeneration. All of these processes may be affected by medications. Some drugs can affect the proliferation of primary callus tissue, others can affect the differentiation of chondrocytes or osteoblasts, formation of capillaries, sensitivity to mechanical input, etc. Therefore, the subject of drugs and fracture repair not only includes pharmacology and orthopedics, but also includes a wide scope. Repair steps after bone damage include: stage 1: (swelling stage), stage 2: (primary bone repair): over the next 4 to 21 days, a callus is formed around the broken bone. In this stage, a substance called collagen gradually replaces the blood clot. Step 3: (secondary bone repair) approximately two weeks after the fracture, cells called osteoblasts start working. These cells cause new bone to fuse and provide minerals needed for bone strength. Step 4: (reconstruction step): in this stage, cells called osteoclasts make the needed changes and adjustments. These cells break down any extra bone that is formed during this healing phase to return the bone shape to its normal status. In current veterinary and also human orthopedics, bone grafts are used for stimulation of fractures healing, accelerate joint fusion and repair of bone defects. Native grafted bone in addition to healing stimulator substances, contains cells that do not stimulate immune reactions and do not transmit infectious diseases. Currently, due to the problems of autologous bone grafting, the desire to use non-autologous bone grafts such as allograft and xenograft has increased. Kinetic hydroxyapatite, tricalcium phosphate and their both combination are among the common materials for bone grafting. Hydroxyapatite works as a scaffold for the growth of bone-forming cells; tarantula cubensis is an extract that is widely used in the treatment of tumors, smallpox, septicemia and toxemic diseases. Also, other materials that are used as substitutes, after being implanted at the site of bone lesions, induce the differentiation of undifferentiated mesenchymal cells present at the site of the lesion into chondrocytes or immature bone cells, and finally, the defects are successfully repaired. Manuscript profile
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        87 - An overview of sampling, sample size and data collection methods in veterinary research
        Dariush Saadati Samira Saadat jou Ali Anusha
        At the beginning of any study, these questions usually come to the researcher's mind; How many samples should be taken to conduct this study? How are these samples selected from the target population? How I can collect the required data? In this article, we are going to More
        At the beginning of any study, these questions usually come to the researcher's mind; How many samples should be taken to conduct this study? How are these samples selected from the target population? How I can collect the required data? In this article, we are going to answer these questions. In order to choose the appropriate sample size, attention should be paid to the statistical method with which the data is to be analyzed. In the surveys, the researcher intends to estimate the desired average or prevalence in the population with 95% confidence interval. There are two formulas for determining the sample size in surveys that are referred to. In studies, the aim is to compare the average or prevalence between different groups. In each study, according to which statistical test to use for data analysis, there is a specific formula for determining the sample size, some of which are mentioned in this article. In order to choose the sampling method from a statistical point of view, attention should be paid to the type of research, in surveys and cross-sectional observational studies, the samples should be randomly selected from among the members of the population. Otherwise, these samples will not be representative of the target population. But in interventional studies, random sampling method is not considered. Rather, there are inclusion criteria, and any person or animal (in veterinary studies) who meets these criteria can enter the study. After the members enter the intervention study, these members should be randomly assigned to different treatments. The required data to conduct research can be collected through examination, observation, experiments or interviews. A questionnaire must be designed for the interview. In designing the questionnaire, attention should be paid to the validity and reliability of the questions. Manuscript profile
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        88 - An Overview of Artificial Intelligence Applications in Prediction and Diagnosis of Diseases Occurrence in Veterinary Medicine: Challenges and Techniques
        Mahdi Bashizadeh Parham Soufizadeh Mahdi Zamiri Ayda Lamei Matin Sotoudehnejad Mahsa Daneshmand Melika Ghodrati Erika Isavi Hesameddin Akbarein
        Early diagnosis of diseases is one of the main goals of health and wellness centers. Timely diagnosis can reduce the potential damage of diseases. The importance of this issue in veterinary medicine multiplies due to its combination with economic goals. Therefore, a pre More
        Early diagnosis of diseases is one of the main goals of health and wellness centers. Timely diagnosis can reduce the potential damage of diseases. The importance of this issue in veterinary medicine multiplies due to its combination with economic goals. Therefore, a predictive approach is necessary for early diagnosis of diseases. This approach should be evidence-based and highly accurate. It should also be economically efficient. Artificial intelligence is the simulation of human intelligence and judgment by a computer or a robot that is programmed or trained to perform tasks that normally need human abilities. The emergence of artificial intelligence and machine learning techniques in today's world has improved the existing functions in health care systems. So that with the application of this technology, a significant progress has been made in the procedures of event prediction and disease diagnosis, management and health at the macro level, etc. Furthermore, the scope of diagnosable diseases is extensive, encompassing any ailment for which relevant data can be processed by artificial intelligence algorithms. The trained model has the capability to diagnose a wide range of diseases, with accuracy contingent upon factors such as disease indicators, collected data, and other pertinent variables. In this review article, the most important applications of artificial intelligence in veterinary medicine will be mentioned, and in general, these applications will be examined in various fields such as diagnosis of common diseases, differential diagnosis, prediction of disease occurrence, veterinary diagnostic imaging techniques, veterinary clinical pathology, etc. In addition, the challenges in this field will also be mentioned. This article is a review of recent studies in this fiel. Manuscript profile
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        89 - Evaluation of Diagnostic and Screening Test in Veterinary Medicine
        Mohammad Arad Zandieh Fateme Sheikhian Hamid Sharifi Hesameddin Akbarein
        Screening tests are a special type of diagnostic tests that are performed in an apparently healthy population. The purpose of performing diagnostic tests is to correctly diagnose patients, distinguish affected animals from healthy animals, distinguish between cases and More
        Screening tests are a special type of diagnostic tests that are performed in an apparently healthy population. The purpose of performing diagnostic tests is to correctly diagnose patients, distinguish affected animals from healthy animals, distinguish between cases and controls, and distinguish between normal and abnormal cases. Screening tests should be simple, cheap, rapid and valid. Diagnostic and screening tests are mainly used in the monitoring of diseases. Related terms to the evaluation of these tests, including sensitivity, specificity, positive and negative predictive value, accuracy and precision, as well as concepts such as the golden standard, because they are often used interchangeably or misinterpreted, it is especially important to learn them. Also, due to the fact that gold standard tests are often more expensive and time-consuming, incomplete diagnostic tests are used, which can be calculated by calculating the sensitivity and specificity of the actual and apparent prevalence obtained by the diagnostic test. However, if the golden standard test is not available, other methods are used to evaluate the tests, including the Kappa index test. The interpretation results of these tests provide a comprehensive and evidence-based approach to clinicians and experts, which ultimately leads to more accurate, comprehensive, cheaper and faster monitoring. In this review article, with a complete and comprehensive review of the conventional concepts in the evaluation of diagnostic tests, along with the solution of practical examples, we will expand and provide a comprehensive presentation of these concepts. Also, the latest original studies that have been done in the field of evaluation of diagnostic tests will also be reviewed in this article. Manuscript profile
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        90 - Data Analyses in Veterinary Research & Practice
        Negin Esfandiary MohammadArad zandieh
        Researchers can interpret and analyze livestock problems and diseases by using data obtained from different characteristics of animals and their environment. The pivotal role of statistical analysis of data in the field of veterinary research & practice is inevitable. I More
        Researchers can interpret and analyze livestock problems and diseases by using data obtained from different characteristics of animals and their environment. The pivotal role of statistical analysis of data in the field of veterinary research & practice is inevitable. In this review article, shedding light on its significance in unraveling complex patterns and drawing reliable conclusions from diverse datasets. The veterinary domain, characterized by a spectrum of species and inherent biological variability, necessitates robust statistical methodologies to discern meaningful insights. In order to make inferences about disease causation or a researcher's hypothesis, data must be categorized and the goal is to decide whether the groups are statistically different or not. Finally, using a suitable statistical test, the research hypothesis is rejected or accepted, and finally the necessary interpretations are made. The researcher can decide what data should be collected and how. In practice, in this case, the researcher's hands are open and they can make the best possible decision, but often prospective data collection is costly and time-consuming. Another mode is retrospective research, which is often based on data collected by veterinarians from slaughterhouses, laboratories, clinics, inoculation centers, etc. or from other organizations and institutions. The article explores a range of statistical techniques applied in veterinary research and practice, including data normalization, hypothesis test, parametric and non-parametric test, regression and coefficient test, and validity in veterinary medicine. These futures has shedding light on animal interactions and patterns. Ultimately, this review article serves as a comprehensive guide for researchers and practitioners in veterinary science, offering insights into the nuanced application of statistical analyses. By navigating the complexities of veterinary data, it aims to empower the scientific community to leverage statistical tools effectively, ultimately advancing the quality and reliability of research in veterinary medicine. Manuscript profile
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        91 - Interventional (Experimental) Studies in Veterinary Research & Practice
        Alireza Bahonar Marzieh Faezi Zahra Boluki
        Interventional studies , especially in laboratory experimental researches , constitute a significant portion of the theses conducted in veterinary faculties across the country . The importance of these study designs in applied research and development underscores More
        Interventional studies , especially in laboratory experimental researches , constitute a significant portion of the theses conducted in veterinary faculties across the country . The importance of these study designs in applied research and development underscores the necessity for students and researchers to be familiar with this design . This article begins with a brief history of this type of study . It then proceeds to introduce various types ( laboratory , clinical trials , field trials , social trials , quasi-experimental studies ) , the different phases of this design ( pharmacological and toxicity testing , initial testing for potential therapeutic and safety effects , clinical evaluation stage , post-marketing evaluation ) , and its various methods (parallel design , crossover design , sequential design , factorial design ) . This article also discusses the required sample size for conducting a study , criteria for entry and exit of study participants or animals , blinding and medical ethics . Given the importance of clinical trials , especially in terms of ethical considerations in research , the registration of this type of study after proposal development is also mentioned . This article refers to some examples of interventional studies published in Iran and worldwide so that students and researchers can use these designs as models . It is expected that the reader could critically read these type of articles and reports , published in scientific texts and play an effective role in conducting an experimental ( interventional ) study . Manuscript profile
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        92 - Observational Studies in Veterinary Research & Practice
        Alireza Bahonar Marzieh Faezi Zahra Boluki
        One of the most important applications of epidemiology is the investigation of the causes of diseases. In this regard, the appropriate design of study to approach the causes and risk factors of a disease is vital. Observational studies are a category of studies that hel More
        One of the most important applications of epidemiology is the investigation of the causes of diseases. In this regard, the appropriate design of study to approach the causes and risk factors of a disease is vital. Observational studies are a category of studies that help the researcher in identifying risk factors for disease occurrence and quantifying the effect of these factors on it, thereby influencing its control within the population. These studies are conducted through observing the natural behavior of disease in the population. Accurate and precise data collection (a part that receives less attention in the country) forms the cornerstone of these studies, requiring special attention from educational, extension, and research centers. In this article, various types of observational studies are initially introduced in general terms. Subsequently, cross-sectional, case-control, and cohort studies, as the three main types of observational studies, are comprehensively explained. The methods of grouping for study entry, calculation of minimum sample size, applications, and advantages and disadvantages of each study are described in detail. Additionally, the capabilities that each type of these studies provides to the researcher for interpreting the causality of the occurrence or the desired outcome in the study are provided at the end of each section. After introducing the implementation method of each study, depending on the case, references to three or four articles with similar study designs are provided to serve as examples of observational studies as a model. It should be noted that these types of studies are foundational for conducting intervention studies, and creating infrastructure for data recording and analysis is necessary for conducting these studies. Manuscript profile
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        93 - Problem-solving and Futures Studies in Veterinary Programs and Services
        Alireza Bahonar Hamid Sharifi
        The increase in population and the need to supply foodstuffs have raised the importance of animal health and veterinary activities more than ever before in the country's food security and development. In this paper, which focuses on veterinary activities in the field of More
        The increase in population and the need to supply foodstuffs have raised the importance of animal health and veterinary activities more than ever before in the country's food security and development. In this paper, which focuses on veterinary activities in the field of food-producing livestock, the concepts of need, supply, and demand are defined, and the methods of determining and prioritizing health needs in the livestock population of the country are presented. In the context of problems in setting priorities, there are also important points such as livestock population statistics, lack of human resources, rapid management changes, economic factors, management considerations, the traditional structure of animal husbandry, insufficient training of producers, and technical health officials of livestock farms, lack of inter-sectoral cooperation and necessary support. From the country's veterinary organization, the lack of sufficient information about diseases and animal health status in neighboring countries, especially Iraq and Afghanistan, and the weakness of border and interprovincial quarantine systems have been noted. Factors affecting the use of animal health services points such as access to services, feeling of need or demand, assurance of quality, price and cost of services and insurance coverage have been mentioned. On the other hand, in recent decades, issues such as climate change, changes in international laws and regulations related to animal health and environment, transgenic products, bioterrorism, and drought, each of which affects the health and livestock production in some way, the need to pay attention to Proposes futures studies. Futures studies are a science that helps to better see these changes and prepare for them. The emergence of some new fields such as artificial intelligence, remote medicine and veterinary medicine (Telemedicine), personalized medicine and veterinary medicine, the emergence of robots in medicine and veterinary medicine, etc. paid attention. The sum of these issues should make us think about how much preparation there is for the future and these changes. It is suggested to make changes in the important fields of veterinary medicine such as education and research, veterinary structures at the national and international levels, and jobs related to veterinary medicine, in line with foresight and futurology. Manuscript profile