ترمیم و بازسازی تاندون با نانوذرات
محورهای موضوعی : علوم جراحی دامپزشکی شامل جراحی های بافت های سخت و نرمسارا جوانمردی 1 * , دارا عزیزی 2
1 - دانشگاه تبریز
2 - دانشگاه تبریز
کلید واژه: نانوذرات, جراحات تاندونی, داربست,
چکیده مقاله :
بافت تاندون دارای پتانسیل بازسازی محدودی می‌باشد و معمولاً تشکیل بافت اسکار باعث ایجاد خواص مکانیکی پایین می شود. نانوذرات را می توان به طرق مختلف برای بهبود ترمیم و بازسازی تاندون استفاده کرد که عبارت اند از ساخت داربست (افزایش قدرت وتحمل و یا خاصیت ضد چسبندگی، خواص ضد میکروبی و ضد التهابی) تا ژن درمانی. هدف این مقاله جمع بندی مهم ترین مطالعات مرتبط با کاربرد بالقوه نانوذرات برای بازسازی بافت تاندون است.
Tendon tissue has limited regeneration potential and usually the consequent formation of scar tissue causes inferior mechanical properties. Nanoparticles could be used in different way to improve tendon healing and regeneration, ranging from scaffolds manufacturing (increasing the strength and endurance or anti-adhesions, anti-microbial, and ante inflammatory properties) to gene therapy. This paper aims to summarize the most relevant studies showing the potential application of nanoparticles for tendon tissue regeneration.
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