Pleomorphic Rhabdomyosarcoma on Maxillary Region in a Persian cat
Subject Areas : Clinical Complications and their Treatments
Keywords: Pleomorphic, Rhabdomyosarcoma, Maxilla, Persian cat,
Abstract :
Rhabdomyosarcomas are the skeletal and cardiac tumors and one of the easily metastatic tumors. A 10 years old DSH cat was referred to the surgery department of veterinary clinic with anorexia, halitosis, excessive salivation and a mass on left buccal region. After general anesthesia, the mass was resected from 5mm of healthy margin. In histopathology investigation, H&E staining, there is a complex of big, small and round rhabdomyocytes. Masson's trichrome staining showed that tumoral tissue was muscular. SMA was positive in many of tumoral cells. Desmin was positive in 60% of tumoral cells and myoglobin was positive in 80% of cells and moderate differentiated pleomorphic rhabdomyosarcoma was reported.
1. American Cancer Society (2013): What is rhabdomyosarcoma. Erişim adresi: http://www.cancer.org/cancer/rhabdomyosarcoma/detailedguide/rhabdomyosarcoma-what-is-rhabdomyosarcoma
2. Beck ER, Withrow SJ, McChesney AE, Richardson RC, Henderson RA, Norris AM, Caywood DD, Klausner JS, Harvey HJ, Holmberg DL (1986): Canine tongue tumors: a retrospective review of 57 cases. J Am Anim Hosp Assoc, 22, 525-532.
3. Brockus CW, Myers RK (2004): Multifocal rhabdomyosarcomas within the tongue and oral cavity of a dog. Vet
Pathol, Vol.41, 273-274.
4. Castero, B.G. A comparative review of canine and human rhabdomyosarcoma with emphasis on classification and pathogenesis. Vet. Pathol., Vol.55, p.806-826, 2013.
5. Cooper BJ, Valentine BA (2002): Tumors of muscle. 341-359, 361-362.
6. Ergin I., Ahlat O., Oto C., (2014): Oral Pleomorphic rhabdomyosarcoma in a dog with the long metastasis. Ankara Univ Vet Fak Dreg, 61, 225-227.
7. Gandi L, Vivekanand S (2012): Maxillofacial rhabdomyosarcoma in the canine maxillofacial area.Vet World, 5, 565-567.
8. Ginel PJ, Martin de las mulas J, Lucena R, Millan Y, Novales M (2002) Skeletal muscle rhabdomyosarcoma in a dog, 151, 736-738.
9. Kim DY, Hodgin EC, Cho DY, Varnado JE (1996) Juvenile rhabdomyosarcomas in two dogs, Vet Pathol, 33,447-450.
10. Lascelles BDX, McInnes E, Dobson JM, White RAS (1998): Rhabdomyosarcoma of the tongue in a dog. J Small Anim Pract, 39, 587-591.
11. Meuten, Donald J, Tumors in Domestic Animals, 5th Edition, (2017): Wiley Blackwell Pub., p512.
12. Nakaichi M, Itamoto K, Hasegawa K,
Morimoto M, Hayashi T, Une S, Taura Y, Tanaka K (2007) Maxillofacial rhabdomyosarcoma in the canine maxillofacial area. J Vet Med Sci, 69, 65-67.
13. Rosa MR, Amorim RFB, Carneiro FP, Benatto N, Barriviera M, Miguel MCC (2010) Aggresive spindle cell rhabdomyosarcoma in an 11-month old boxer dog. J Vet Med Sci, 72, 1363-1366.
14. Yamate J, Murai F, Izawa T, Akiyoshi H, Shimizu J, Ohashi F, Kuwamura M (2011) A Rhabdomyosarcoma Arising in the Larynx of a Dog, J Toxicol Pathol, 24, 179-182