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        1 - Laboratory diagnosis of liver disease in small animal practice
        Saba Ahmadi Morteza  Hasanabadi Mehrdad Mohri
        Today’s accurate diagnosis of disease requires using of different diagnostic and paraclinical methods. Diagnosis of liver disease was a serious challenge both in medicine and veterinary medicine from the past. Clinical biochemistry is one of the main parts of diagnostic More
        Today’s accurate diagnosis of disease requires using of different diagnostic and paraclinical methods. Diagnosis of liver disease was a serious challenge both in medicine and veterinary medicine from the past. Clinical biochemistry is one of the main parts of diagnostic methods. Liver function is evaluated by measuring the variables such as excreting and metabolic functions and enzymes. Because of large functional reserve of liver, symptoms of liver disease appear after loss of huge number of hepatocytes, therefore using of laboratory methods with high specificity and sensitivity could be helpful. None of existing laboratory methods has all characteristics mentioned above. It seems that using different laboratory methods of liver function beside other diagnostic methods such as sonography, cytology and … could be an appropriate approach for reaching a diagnosis of hepatobiliary disease. Current article reviews the perfect utility of liver function tests for general diagnosis of liver disease. Manuscript profile
      • Open Access Article

        2 - Laboratory diagnosis of renal diseases in small animal practice
        Morteza  Hasanabadi Saba Ahmadi Mehrdad Mohri
        Common tests for evaluating renal function include the measurement of urea and creatinine. However, indirect markers for the determination of GFR, such as Cystatin C and Symmetrical Dimethyl Arginine, are in developing. In the next step, for diagnosis and treatment, azo More
        Common tests for evaluating renal function include the measurement of urea and creatinine. However, indirect markers for the determination of GFR, such as Cystatin C and Symmetrical Dimethyl Arginine, are in developing. In the next step, for diagnosis and treatment, azotomia should be classified into one of the pre-renal, renal and post-renal groups. In the next step, it is necessary of categorizing the disorder to acute or chronic failure. Diagnosis of chronic or acute illness is done based on the history of the patient and physical examination. Weight loss and non-regenerative anemia may be signs of patients with CKD.Another useful test is urine analysis. A urine test prepared valuable information about azotemia and its causes. Additional tests are also available to diagnose kidney failure such as phosphorus, calcium, potassium, acid-base status, cholesterol, urine albumin, and GGT to urine creatinine ratio. Newbiomarkers such as Cystatin C, a Kidney injury molecule, and Neutrophil gelatinase-associated Lipocalinare also being studied and commercialized for early diagnosis of kidney disease, but they have not yet been clinically available for veterinary use. Manuscript profile