Sepsis is a complex and dynamic syndrome and it is a medical and economic challenge. To learn more about pathophysiology of this syndrome, animal models have been introduced. Poly microbial sepsis induced by cecal ligation and puncture is the gold standard model of this More
Sepsis is a complex and dynamic syndrome and it is a medical and economic challenge. To learn more about pathophysiology of this syndrome, animal models have been introduced. Poly microbial sepsis induced by cecal ligation and puncture is the gold standard model of this condition. The purpose of this study was introducing a new method of septic peritonitis with laparoscopic assisted cecal ligation and cauterization (CLC) in rabbit model. This study included two groups of adult male New Zealand white rabbits:
Control group (4rabbits): exploratory laparoscopy was performed and the cecum was grasped from the distal of ileocecal valve using an atraumatic forceps and pulled out from the trocar entry site. CLC group (4 rabbits): the cecum was ligated and two sites of cecum were cauterized from antimesenteric to mesenteric surface of cecum. Before and during 24 hours after the operation, heart rate, rectal temperature and respiratory rate of rabbits were monitored. Ultrasonography, CBC, peritoneal fluid analysis and bacterial culture was checked 24 hours after the surgery. Statistical analysis of the data in CLC group rabbits showed a significant increase in heart rate 6 and 18 hours after surgery (tachycardia) and increase in respiratory rate from 6 to 24 hours after surgery (tachypnea). In addition, a significant decrease in glucose of serum was observed. Bacterial culture was positive and peritoneal analysis of all rabbits in CLC group indicated the presence of bacteria and infection.
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Minimally invasive surgeries are one of the most important revolutions in the history of surgery. recently, different methods of this type of surgery are widely used in medicine and veterinary medicine. With recent advances in minimally invasive surgery, a variety of su More
Minimally invasive surgeries are one of the most important revolutions in the history of surgery. recently, different methods of this type of surgery are widely used in medicine and veterinary medicine. With recent advances in minimally invasive surgery, a variety of surgical methods have been introduced. Laparoscopic gallbladder resection is the most common type of minimally invasive surgery and many other surgeries have been introduced in the same way. This article introduces new methods in minimally invasive surgery. The further use of this type of surgery depends entirely on the development of new technologies in this field.
The success of surgical procedures in the treatment of diseases is always measured by the amount of pain and trauma that the surgical method inflicts on the patient. Reducing these two factors has led to the progression and change surgical methods with minimal invasions in general and laparoscopic surgeries particularly in the last century.
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Objective- While many of studies have evaluated effects of trocar on incision characteristics non has taken the design of the cannula into consideration. This study was conducted to figure out the type of cannula design which is associated with a better healing at the i More
Objective- While many of studies have evaluated effects of trocar on incision characteristics non has taken the design of the cannula into consideration. This study was conducted to figure out the type of cannula design which is associated with a better healing at the insertion site, and to investigate if the size of incision in the port site has an effect on the healing process.
Procedure-6 trocars were inserted in each dog. five animals were used, allowing the total number of 10 insertions for 7 mm incisions and threaded cannula (group A), 10 insertions for 10 mm incision and threaded cannula (group B) and 10 for 10 mm incision and smooth cannula (Group C), which constituted 3 groups of study.
Results-Macroscopic and Histopathology comparison between group A and group B revealed significantly higher degenerative changes and necrosis in the dermal and muscle layer and a higher loss of the peritoneal lining in group A than B. Hemorrhage in the dermal layer of the skin and acute inflammatory reaction was significantly higher in group B compared with C .
Conclusions - This study showed that a smaller incision than the trocar’s external diameter has destructive effects on the tissues. Moreover, using a trocar with a threaded cannula can have harmful effects on the surrounding tissues and it is considered more destructive than a smooth cannula.
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